The expression of the B- cell marker mb-1 (CD79a) in Hodgkin's disease. Histopathology 1994; 24; 511±515.Korkolopoulou P, Cordell J, Jones M, et al. The expression of the B-cell marker mb-1 (CD79a) in Hodgkin's disease. Histopathology 1994;24:511-15....
Diffuse large B-cell lymphoma (DLBCL) lines of the germinal center B-cell (GCB) type express a BCR, which can signal after crosslinking, but are unaffected by BCR pathway targeting toxic to lines of the activated B-cell (ABC) DLBCL subtype: knockdown of BCR signaling mediators (BTK, CD...
Marginal zone B cell lymphoma (MZBCL) represents a distinct subtype of B cell non-Hodgkin's lymphoma, which has been recently recognized and defined as a d... J Dierlamm,C Rosenberg,M Stul,... - 《Leukemia》 被引量: 218发表: 1997年 Gastric MALT lymphoma: a model of chronic inflammat...
aThe t-SNE projection of 8632 B cells from TNBC patients shows 13 major cellular clusters at a higher resolution.bSelected marker genes to define each B cell cluster.cThe distributions of 13 clusters in each patient sample (upper panel: PBMC; lower panel: TNBC). X represents B cell clusters...
2. Visco C, et al. Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification in diffuse large B-cell lymphoma: a report from the International DLBCL...
3a). As shown, differentially expressed genes in each cell subset was divided into upregulated and downregulated genes according to the trends in their expression as the disease proceeded (Fig. 3a, b). KEGG analysis of differentially expressed genes in each cell subtype was carried out, ...
The diffuse large B cell lymphoma(DLBCL) is the most frequent type of non-Hodgkin lymphomas around the world and in all age groups. DLBCL is a heterogeneous diagnostic category consisting of molecularly distinct subtypes differing in gene expression, oncogenic aberrations and clinical outcomes. The ...
Randomized Phase 2 Open-Label Study of R-CHOP ± Bortezomib in Patients (Pts) with Untreated Non-Germinal Center B-Cell-like (Non-GCB) Subtype Diffuse Large Cell Lymphoma (DLBCL): Results from the Pyramid Trial (NCT00931918) Background Addition of bortezomib to R-CHOP (VR-CHOP) may overcom...
By single-cell RNA sequencing (scRNA-seq), we not only find that activated B cells are significantly depleted in CRC with LM, but also find a subtype of B cells developed from activated B cells, namely immature plasma cell population alpha (iMPA), highly correlated with metastasis. ...
cell clusters were manually annotated based on expression of reference marker RNAs. scB clusters were unique to FL samples. Cells in the GC B cluster were assigned to the same cluster as scB08 but derive from rLN samples and are labeled separately for clarity.CDendrogram of Pearson correlation ...