【德鲁大学2024秋免疫学课程】Lecture 21 T cell Development 黄金矿工2001 1 0 【德鲁大学2024秋免疫学课程】Lecture 28 Peripheral B Cell Responses 黄金矿工2001 1 0 【德鲁大学2024秋免疫学课程】Lecture 36 Transplantation 黄金矿工2001 3 0 【德鲁大学2024秋免疫学课程】Lecture 8 Flow Cytometry 黄金矿工...
1、Nature : 肠道生发中心B细胞选择的可调动力学 2020年10月28日,来自美国洛克菲勒大学Gabriel D. Victora和Daniel Mucida课题组合作的在《自然》杂志上发表了题为“Tunable dynamics of B cell selection in gut germinal centres.”的最新研究成果。他们揭示了肠道生发中心B细胞选择的可调动力学。通过结合多色“Bra...
近日,美国华整顿大学医学院Marion Pepper团队在Immunity杂志发表了题为Interleukin-4 downregulates transcription factor BCL6 to promote memory B cell selection in germinal centers的文章。作者发现GCB细胞中的IL-4细胞因子信号通过负向自动调节直接下调转录因子BCL6,从而将细胞从GCB程序中释放并促进MBC的形成,这会...
2月17日,来自澳大利亚昆士兰大学的余迪团队(论文第一作者:陈之岸博士)和来自美国匹兹堡大学的Mark Shlomchik团队(论文第一作者:罗威博士)在Science Immunology同步发表了题为Heparan sulfate regulates IL-21 bioavailability and signal strengt...
人CD3+T细胞阳选试剂盒 CD3+ T Cell Selection Kit 人CD3+T细胞分选试剂盒,阴选 CD3+ T Cell Isolation Kit 人CD4+T细胞阳选试剂盒 CD4+ T Cell Selection Kit 人CD4+T细胞分选试剂盒,阴选 CD4+ T Cell Isolation Kit 人CD8+T细胞阳选试剂盒 CD8+ T Cell Selection Kit ...
3. D. Dominguez-Sola et al., The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nat. Immunol. 13, 1083–1091 (2012). doi: 10.1038/ ni.2428; pmid: 23001145 4. D. P. Calado et al., The cell-cycle regulator c-Myc is essential for the ...
[9] Mesin L , Ersching J , Victora G D . Germinal Center B Cell Dynamics[J]. Immunity, 2016. [10] Nakagawa R , Toboso-Navasa A , Schips M , et al. Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell...
Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells. Nat. Immunol. 16, 663–673 (2015). Article CAS PubMed Google Scholar Shlomchik, M. J. & Weisel, F. Germinal center selection and the development of memory B and plasma...
Easily and efficiently isolate highly purified mouse B cells from single-cell suspensions of splenocytes or other tissue samples by immunomagnetic negative selection, with the EasySep™ Mouse B Cell Isolation Kit. Widely used in published research for more than 20 years, EasySep™ combines the...
Fig. 4: Association of selection with infiltrating T cell fraction. - 图片说明 ◉ 火山图展示了泊松模型的结果,该模型预测了非同义突变的数量作为TCRA T细胞比例和其他协变量(年龄、肿瘤突变负荷、性别和疾病类型)的函数。◉ 图表显示了TCRA变量的估计值和−log10(P),突出了那些显著依赖于T细胞免疫浸润的...