B cell marker genesNeoadjuvant immunotherapyNon-small cell lung cancerSingle-cell RNA sequencing.Background: Neoadjuvant immunotherapy has evolved as an effective option to treat non-small cell lung cancer (NSCLC). B cells play essential roles in the immune system as well as cancer progression. ...
In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cel...
upregulated genes in CD8+ T cells and NK cells were also enriched in Alzheimer’s disease, ranking second and fifth, respectively. Immediately,the investigation value of B cells in AD stands out of other cell subsets
Objective: This study amied to investigate the prognostic characteristics of triple negative breast cancer (TNBC) patients by analyzing B cell marker genes based on single-cell and bulk RNA sequencing. Methods: Utilizing single-cell sequencing data from TNBC patients, we examined tumor-associated B ...
sce <- RunPCA(object = sce, pc.genes = VariableFeatures(sce)) # DimHeatmap(sce, dims = 1:12, cells = 100, balanced = TRUE) # ElbowPlot(sce) sce <- FindNeighbors(sce, dims = 1:15) sce <- FindClusters(sce, resolution = 0.2) ...
B cell development in specific organs and niche environments is coordinated by expression of transcription factors [2, 3, 4, 5, 6, 7]. Each cell fate depends on the activation and silencing of certain B cell genes and this developmental state can be assayed by the expression ...
from human lymph nodes, using marker genes defined from DLBCL tumors。 五种状态的B细胞都在正常细胞中存在,而且We observed specificity of S1 for germinal center (GC) B cells, S2 and S3 for pre-memory B cells, S4 and S5 for pre-plasmablasts, and S4 for light zone B cells(每种状态的B细...
查看marker表达情况 参考: 多分组单细胞转录组测序样本第一层次未整合和整合数据的B细胞细分对比 B细胞细分亚群 仅仅是区分了 B细胞和 Plasma细胞。 现在我们就从文献《Single-cell landscape and clinical outcomes of infiltrating B cells in colorectal cancer》来说一下B细胞的细分亚群。它是一个单细胞数据挖掘文...
英文名称: Recombinant B-Cell Activating Factor (BAFF) 保质期: 避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。 保存条件: 2-8°C不超过一个月,-80°C不超过12个月 B-细胞激活因子(BAFF)重组蛋白多年致力于重组蛋白表达,抗体制备研究,我们目前拥有大量的商业化表达载体质粒包括多种标签质粒...
The polymorphisms of pLDH genes was analyzed using the software MEGA version 7.0.26 and DnaSP version 5.10, and the B⁃cell epitopes were predict⁃ ed in pLDH peptides using the Immune Epitope Database (IEDB). Results The sequences of P. vivax LDH (PvLDH), P. falci⁃ parum LDH...