B-cell lymphoma is a type of blood cancer that affects the B lymphocytes of the immune system. They usually arise in the lymph nodes or in other lymphoid tissue, such as the spleen, bone marrow, blood or other organs. B-cell lymphomas are composed of large B lymphoid cells whose nuclear...
[7] Shimin Hu,Zijun Y,Xu-Monette,et al.CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium P...
The prognosis depends on the histologic type, stage, and treatment. Next: Background What to Read Next on Medscape Related Conditions and Diseases Diffuse Large B-Cell Lymphoma (Non-Hodgkin Lymphoma) Staging Diffuse Large B-Cell Lymphoma (DLBCL) Diffuse Large B-Cell Lymphoma (Non-Hodgkin ...
Lymphoma, T-CellThe B-cell lymphomas (BCLs) represent 80% to 90% of non-Hodgkin lymphomas in the Western world and include multiple lymphoma subtypes with different biologies, natural histories, morphologic characteristics, immunophenotypes, genetic features, prognoses, and responses to therapy. 1 ...
DLBCL-COO基因检测可用于弥漫性大B细胞淋巴瘤分子分型与预后评估 弥漫性大B细胞淋巴瘤（diffuse large B-cell lymphoma, DLBCL）是淋巴瘤中最常见的亚型。在中国，每年新增淋巴瘤患者约为10万人，其中，DLBCL约占所有淋巴瘤的33%[1]。2016修订版WHO淋巴造血组织肿瘤分类根据全基因组表达谱的不同，将DLBCL按照细胞...
#弥漫大B细胞淋巴瘤#（Diffuse large B-cell lymphoma, DLBCL）是B细胞起源、具侵袭性临床表现、需高效力的化学治疗的恶性淋巴瘤【1】。目前广泛应用于临床的DLBCL预后评估标准是改良国际预后指数（National Comprehensive Cancer Network-International Prognostic Index, NCCN-IPI）【2】。但是，NCCN-IPI仅纳入了一些...
[7] Basso K , Dalla-Favera R . Germinal centres and B cell lymphomagenesis[J]. Nature Reviews Immunology. [8] Zhang Y , Garcia-Ibanez L , Toellner K M . Regulation of germinal center B-cell differentiation[J]. Immunological reviews, 2016, 270(1):8. ...
www.nature.com/scientificreports OPEN received: 02 April 2015 accepted: 05 January 2016 Published: 09 February 2016 The distinct clinical features and prognosis of the CD10+MUM1+ and CD10−Bcl6−MUM1− diffuse large B-cell lymphoma Ting-Xun Lu1,2,*,Yi Miao1,*, Jia-Zhu Wu...
This review summarized the research progress on DNA methylation, histone modification and miRNA as well as their roles in the development, treatment and prognosis of B-cell lymphomas. KEYWORDS: B-cell lymphoma;DNA methylation;Histone modification;MicroRNA Corresponding author: Pan Yun, Email: moc....
Low serum apolipoprotein A1 level predicts poor prognosis of patients with diffuse large B-cell lymphoma in the real world: a retrospective study[J]. BMC Cancer, 2024, 24(1): 62. [5] Hanahan D., Weinberg R. A. Hallmarks of cancer: the next generation[J]. Cell, 2011, 144(5): 646...