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B-cellacute lymphoblastic leukemiais acancerthat affects your "B lymphocytes" -- whiteblood cellsthat grow in the soft center of your bones, called marrow. B lymphocytes are supposed to grow into cells that help you fight infections. But in this disease, they turn into "leukemia" cells that...
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Philadelphia chromosome-positive acute lymphoblastic leukemia (PH + ALL) is the most common cytogenetic abnormality of B-ALL in adults and is associated with poor prognosis. Previously, the only curative treatment option in PH + ALL was allogeneic hematopoietic stem cell transplantation (Allo...
Clinical use of blinatumomab for B-cell acute lymphoblastic leukemia in adults. Ther Clin Risk Manag. 2016;12:1301-10.Lee KJ, Chow V, Weissman A, Tulpule S, Aldoss I, Akhtari M (2016) Clinical use of blinatumomab for B- cell acute lymphoblastic leukemia in adults. Ther Clin Ri...
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Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults. The oncogenic mechanisms underlying acute lymphoblastic leukemia (ALL) in adolescents and young adults (AYA; 15-39 years old) remain largely elusive. Here ... - 《Nature Genetics》 被引量: 38发表: 20...
The effector to target (E:T) ratio is based on total T cell number. h, Human IFNγ was measured in NTD-T, MuSK-CAART or CART-19 coculture supernatants (10:1 E:T, 24 h, experiments run using different T cell batches are shown in separate plots). One-way analysis of variance ...