比如小B细胞淋巴瘤/慢性淋巴细胞白血病（SLL/CLL）某些病例可转化为弥漫大B细胞淋巴瘤（Richter's综合征），滤泡性淋巴瘤、边缘区B细胞淋巴瘤、结节性淋巴细胞为主型霍奇金淋巴瘤等也可转化为弥漫大B细胞淋巴瘤。病理 大B细胞淋巴瘤包括：弥漫大B细胞淋巴瘤，非特指型（Diffuse large B-cell lymphoma,NOS）和其他1...
B cell CLL lymphoma 6 (BCL6)Cell culture and mouse studies suggest inhibiting BCL6 could help treat Gleevec- and Tasigna-resistant ALL. Further details on the research, next steps and licensing status are discussed in the article.SciBX: Science-Business eXchange...
B cell CLL/lymphoma 6 member B (BCL6B) is a novel tumor suppressor silenced in human cancer. In this study, we investigated the functional role and underlying mechanisms of BCL6B in hepatocellular carcinoma (HCC). BCL6B was expressed in normal HCC tissues, but its expression was suppressed...
DLBCL是PPL最常见的组织病理学亚型,CHOP或R-CHOP方案是标准治疗,一般给予6个疗程。对于难治性胰腺DLBCL,二线RICE或R-DHAP方案可改善预后。由于肿瘤体积大,术后胰瘘风险高,手术干预并非PPL的主要治疗选择。但如无法通过非手术方式明确胰腺...
英文名称:B-Cell CLL/Lymphoma 6 Phospho-Ser333 (BCL6 pS333) Antibody,中文名称:细胞cll//淋巴瘤6磷酸血清333((bcl6 ps333)抗体,产品货号:Catalogue No: abx327911,<div><p>BCL6(pS333)抗体是一种抗BCL6(pS333)的兔多克隆抗体。<p>靶点BCL6(pS333)<p>
1.NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines). B-Cell Lymphomas. Version 2.2024 2.中国滤泡性淋巴瘤诊断与治疗指南(2023年版) 3.Jacobson CA, Chavez JC, Sehgal AR, et al. Axicabtagene ciloleucel ...
B-cell lymphoma is a type of blood cancer that affects the B lymphocytes of the immune system. They usually arise in the lymph nodes or in other lymphoid tissue, such as the spleen, bone marrow, blood or other organs. B-cell lymphomas are composed of large B lymphoid cells whose nuclear...
弥漫性大B细胞淋巴瘤（Diffuse Large B-cell Lymphoma，DLBCL）是一种常见的非霍奇金淋巴瘤，占据所有NHL病例的30%至40%。了解其病理特点对于诊断和治疗具有重要意义。本文将详细介绍DLBCL的形态学特征、免疫表型、Ki67水平、生发中心相关标志物以及CD5表达等方面。1. 形态学特征 在形态学上，DLBCL由大B细胞组成，...
10. Angela Sheng, et al. Association of the CLL Comorbidity Index (CLL-CI) and International Prognostic Index (IPI) with Overall Survival (OS) and 1-Year Mortality in Patients (pts) with Relapsed or Refractory (r/r) Large B Ce...