Although no adverse effects have been associated with excess vitamin B12 intake from food and supplements in healthy people, weight loss programs that promote vitamin B12, particularly in injectable form, suggest treatment that is not based on sound evidence". In a pilot study, Bertoglio and colle...
C19A3 gold nanoparticle intradermal microinjectable solution of human C19A3 proinsulin peptide coupled to gold. Enhanced Epidermal Antigen-Specific Immunotherapy Trial -1 (EE-ASI-1) Type 1 Diabetes I Active, not recruiting Cardiff and Vale University Health Board Cardiff, United Kingdom Cyclosporine op...
Merck Animal Health launched the 12-month injectable formulation of BRAVECTO for use in dogs in a number of markets in Europe for the treatment and persistent killing of fleas (Ctenocephalides felis and Ctenocephalides canis) and ticks (Rhipicephalus sanguineus, Ixodes ricinus, Ixodes hexagonus,...
The cost of the LFABs is significant, but the counterbalancing reduction in nephrotoxicity is also valuable and should be considered when choosing an LFAB versus a conventional amphotericin B.40A recent study of the impact of nephrotoxicity of amphotericin B deoxycholate in patients wi...
Enhanced antioxidant capacity of dental pulp-derived iPSC-differentiated hepatocytes and liver regeneration by injectable HGF-releasing hydrogel in fulminant hepatic failure. Cell Transplant. 2015, 24, 541–559. [Google Scholar] [CrossRef] Hakkola, J.; Rysä, J.; Hukkanen, J. Regulation of ...
The June 2013 monograph topics are dimethyl fumarate (BG-12) delayed-release capsules, canagliflozin, ospemifene, aripiprazole extended-release injectable, and dabrafenib. The DUE/MUE is on dimethyl fumarate. 展开 DOI: 10.1310/hpj4806-494 被引量: 10 ...
Interius’s Phase 1 trial (INVISE, Injectable Vectors for In Situ Engineering) will evaluate the safety of a single INT2104 infusion in adults with refractory/relapsing B cell malignancies. The Phase 1 study is a global, two-part, multicenter, open-label, single dose design with a dose esc...
(i.e., young, elderly) and also allow dose-sparing in case of vaccine shortages due to the 6–9 month production time for new vaccines37,39,40. Lastly, while traditionally IN vaccines may not perform as well as injectables, they often are a popular needle-free option, as observed with...
Therefore, even if higher efficacy with axi-cel comes at the cost of higher toxicity, the latter does not undermine the significantly better outcome. Because toxicity might be of greater concern in elderly patients and could counterbalance axi-cel’s higher efficacy, we undertook a planned ...
In 2015, the FDA approved for the first time two human injectable antibodies, alirocumab and evolocumab, for certain patients with uncontrolled high LDL-C level (FDA, 2015a, 2015b). In general these agents have been able to achieve an approximate 50–70% reduction in LDL-C when used ...