Proteomics and pulse azidohomoalanine labeling of newly synthesized proteins: what are the potential applications?AzidohomoalanineBiological studiesProteomicsapplicationnewly synthesized proteinIntroduction: Measuring the immediate changes in cells that arise from changing environmental conditions is crucial to ...
The chemical cleavage of amide(peptide)bonds usually requires harsh conditions.As a result,side reactions and the lack of specificity of chemical amide-bond hydrolysis limits its scope in chemical biology and synthetic applications.Herein,we disclose our results on the selective cleavage of amide ...