Studies on azaspiracid biotoxins. I. Ultrafast high- resolution liquid chromatography/mass spectrometry separations using monolithic columnsThe HPLC system used was an Agilent 1100 (Palo Alto, CA, USA) quaternary liquid chromatography system, with a firmware modification to allow flow rates up to 10...
ChemInform Abstract: Studies Directed Toward the Total Synthesis of Azaspiracid. Construction of the C1—C19 (I) Carbon Backbone and Synthesis of the C10, C13 Nonnatural Transoidal Bisspirocyclic Ring System (II).doi:10.1002/chin.200202254...
J. Forsyth, "Gold(I)-catalyzed bis-spiroketalization: Synthesis of the trioxadispiroketal-containing a-d rings of azaspiracid". Angew. Chem. Int. Ed. 2007, 46(1-2), 279-282.Gold (I)-catalyzed bis-spiroketalization: synthesis of the trioxadispiro-ketal-containing A-D rings of az...
Evans, D A
With a practical synthesis of the ABCD aldehyde in hand(2,Scheme 1),herein we describe our progress that culminated in the synthesis of(+)-azaspiracid-l(1)in 26 linear steps and 2.7% overall yield.As outlined in Scheme 1,the addition of an anomeric sulfone anion derived from 3 to a...
Part I: Synthetic studies toward the southern portion of Azaspiracid-1; Part II: Total synthesis of amphidinolide B and the proposed structure of amphidinolide BOrganic chemistry Part I| Synthetic studies toward the southern portion of azaspiracid -1...
Total synthesis of (+)-azaspiracid-1. Part I: Synthesis of the fully elaborated ABCD aldehyde. Evans, David A.,Kvrn, Lisbet,Mulder, Jason A.,Raymer, Brian,Dunn, Travis B.,Beauchemin, Andr茅,Olhava, Edward J.,Juhl, Martin,Kagechika, Katsuji. Angewandte Chemie - International Edition ...
New insights into the causes of human illness due to consumption of azaspiracid contaminated shellfish. Sci Rep. 2015;5:9818. CentralChevallier O.P., Graham S.F., Alonso E., Duffy C., Silke J., Campbell K., Botana L.M., Elliott C.T. New insights into the causes of human ...
Total synthesis of (+)-azaspiracid-1: part II. Synthesis of the EFGHI sulfone and completion of the synthesis. Angew Chem Int Ed 2007; 46: 4698-703.b. Evans DA, Dunn TB, Kvœrnø L, Beauchemin A, Raymer B, Olhava EJ, Mulder JA, Juhl M, Kagechika K, Favor DA. Total ...
Studies of azaspiracid biotoxins. I. Ultrafast high- resolution liquid chromatography/mass spectrometry separations using monolithic columns. Rapid Communications in Mass Spectrometry, 16, 2298-2305.Volmer, D. A.; Brombacher, S.; Whitehead, B. Studies on Azas- piracid Biotoxins. I. Ultrafast ...