Axonal damage in the central nervous system can lead to significant functional loss. Axonal injury in the spinal cord may result in paralysis. 7 Dendrites Unlike axons, dendrites do not typically have a myelin sheath. The lack of myelination in dendrites reflects their role in signal reception ra...
In this paper we discuss a model from neurobiology, which describes the outgrowth of axons from neurons in the nervous system. The model combines ordinary differential equations, defining the movement of the axons, with parabolic partial differential equations. The parabolic equations model the ...
Axon-glial interactions in the central nervous system. Axon-glial interactions are critical for brain information transmission and processing. In the CNS, this is a function of the major types of glia - astrocytes, oligodendrocytes and novel NG2-glia. This special issue of the Journal of Ana.....
The failure of axons to regenerate in the central nervous system is mainly due to inhibition by the environment, made up of astrocytes and oligodendrocytes, which surrounds regions of damage. Both cell types are inhibitory to axon regeneration, and it seems likely that each will have to be ...
Other forms:axons Anaxonis a thin fiber that conducts electrical impulses away from a neuron, or nerve cell.Axonsare an important part of the nervous system. Your nervous system is what your brain uses to send and receive information about what's going on in and around your body. Neurons,...
Axons are myelinated by Schwann cells in the peripheral nervous system. These glial cells envelop the axons to form myelin sheaths. In contrast, the task of myelination is carried out by oligodendrocytes in the central nervous system. Remarkably, a single oligodendrocyte can myelinate as many as...
F. Message in a bottle: long-range retrograde signaling in the nervous system. Trends Cell Biol. 17, 519–528 (2007). Article CAS PubMed Google Scholar Harrington, A. W. & Ginty, D. D. Long-distance retrograde neurotrophic factor signalling in neurons. Nature Rev. Neurosci. 14, 177–...
Enabling axon regeneration after central nervous system (CNS) injury remains a major challenge in neurobiology. One of the major differences between the injured peripheral nervous system (PNS) and CNS is the pro-and antiregenerative responses of their glial cell populations. In addition to intrinsic...
The axon initial segment in nervous system disease and injury. Eur J Neurosci 2011; 34: 1609–19. 74 Spira ME, Oren R, Dormann A, Ilouz N, Lev S. Calcium, protease activation, and cytoskeleton remodeling underlie growth cone formation and neuronal regeneration. Cell Mol Neurobiol 2001; 21...
Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells Objective Repair of demyelinated axons in diseases such as multiple sclerosis requires activation of the myelination program in existing or newly recruited... S Mi,R Miller,W Tang,... - ...