The presence of an Sos1 inhibitor dissociated glucocorticoid receptor-伪 from RAS/Sos1 complex, that restored the sensitivity to steroids in eosinophils. Administering the Sos1 inhibitor effectively attenuated the experimental allergic rhinitis. Conclusions:CR status was detected in approximately 1/3 ...
Clear cell renal carcinoma(ccRCC) MiR-429-CRKL axis Tumorigenesis SOS1/MEK/ERK/MMP2/MMP9 pathway 1. Introduction Renal cell carcinoma (RCC) is a common malignant tumor originating from renal tubular epithelial cells accounting for about 3% [1] of human malignant tumors, accounting for about 85...
The protective effect of circ-Memo1 knockdown on cell injury after H/R treatment was weakened by miR-17-5p inhibition.Knockdown of circ-Memo1 alleviated H/R injury of HBMVEC cells by regulating the miR-17-5p/SOS1 axis, indicating that circ-Memo1 might be a potential treatment target for...
Altogether, we proposed a novel signaling network in which circ_0042881, induced by EIF4A3, influences the process of BC tumorigenesis and metastasis by miR-217/SOS1 axis.doi:10.1038/s41419-023-06085-4Chenxi Jugrid.412633.10000 0004 1799 0733Department of Medical LaboratoryThe First Affiliated ...
Questions like these will be taken into consideration while analysing how the musical preferences are formed on the individual axis. Thus, 'understanding' rather than 'narration' is the priority of this article that follows the stream of thought in the social sciences.İlhan ERSOY...
H19 overexpression increased the protein level of SOS1, and miR-140-5p directly targeted SOS1.#H19 can activate the Ras-MAPK signalling pathway via the miR-140-5p/SOS1 axis in malignant liver tumour cells.Ya-qun Yuhttps://ror.org/03cmqpr17grid.452806.d0000 0004 1758 1729Department of ...
This study aimed to elucidate the underlying mechanism involving the DNMT1/miR-152-3p/SOS1 axis in regulating the self-renewal and tumor growth of LCSLCs (lung cancer stem-like cells). Materials and methods: Target genes of miR-152-3p were predicted using TargetScan Human 8.0. Self-renewal ...