Sample Participants in all three experiments were recruited on a local subject recruitment platform at the University of Würzburg. The inclusion criterion was age between 18–60, the exclusion criteria were pregnancy and epilepsy (in subjects or near relatives). The samples in experiments 1, 2, a...
The 253G1 human iPSC line was provided by the RIKEN BRC through the Project for Realization of Regenerative Medicine and the National Bio-Resource Project of the MEXT, Japan31. Differentiation of human iPSCs into cardiomyocytes was performed using the previously described protocol32. The iPSCs we...
Keywords: MicroRNA-135b, CAMK2D, EMT, Oligonucleotide therapy, Gastric cancer. IntroductionGastric cancer (GC) is the sixth common cause of cancer globally, with 1,090,000 new cases each year, accounting for 5.6% of all cancers, and the third lead cause of cancer-related human mortalities ...
The vagus nerve may be activated by the gut microbiota, and this stimulation has a significant impact on the brain and on the way people behave. The vagus nerve is a vital element of the sensory route that connects the gastrointestinal tract to the brain. The evidence that the gut microbiota...
Orczykowski ME, Arndt KR, Palitz LE, Kramer BC, Pessina MA, Oblak AL, Finklestein SP, Mortazavi F, Rosene DL, Moore TL. Cell based therapy enhances activation of ventral premotor cortex to improve recovery following primary motor cortex injury. Exp Neurol. 2018;305:13–25. https://doi.or...
“It was the best thing that ever happened in my life. They took me under their wing, and all of the best parts of my life have come from walking into the wrong dorm.”—Jake Muise More about Molokai—geography and culture The island is only 10 miles by 30 miles, roughly 180,000 ...
Recent advances in intensity modulated radiation therapy and its combination with chemotherapy have remarkably improved the efficacy of NPC treatments, especially in the early stage [3,4,5,6]. However, more than 70% of NPC cases are diagnosed as advanced-stage disease, and local relapse and ...
pharmaceuticals Article Targeting Autophagy, Apoptosis, and SIRT1/Nrf2 Axis with Topiramate Underlies Its Neuroprotective Effect against Cadmium-Evoked Cognitive Deficits in Rats Hany H. Arab 1,2 , Ahmed H. Eid 3, Rania Yahia 3, Shuruq E. Alsufyani 1 , Ahmed M. Ashour 4 , Azza A. K. ...