The STDP process partially explains the activity-dependent development of nervous systems, especially with regard to long-term potentiation and long-term depression. [...] History In 1973, M. M. Taylor[1] suggested that if synapses were strengthened for which a presynaptic spike occu...
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Placental development relies on coordinated cell fate decisions governed by signalling inputs. However, little is known about how signalling cues are transformed into repressive mechanisms triggering lineage-specific transcriptional signatures. Here, we
inhibitory effect of higher doses of intraperitoneal GLP-1 (100 nmol/kg)136. Long-term administration of exendin-9 abolishes the feeding-suppressive effect of small intestinal lipid infusion, indicating a role of nutrient-induced endogenous GLP-1 in food intake130,137. As such, selective vagal...
THE EFFECT OF SHORT-TERM REPEATED-EXERCISE STRESS ON THE HYPOTHALAMIC-PITUITARY-ADRENOCORTICAL AXIS IN RATSAn abstract is unavailable. This article is available as a PDF only.doi:10.1249/00005768-198504000-00350DavisJ.M.LambertM.I.Medicine & Science in Sports & Exercise...
Intention of Long-Term Residence:Candidates must have an intention to reside in a designated community for the longer term. While applying, you are required to have a valid recommendation certificate issued by an economic development organization. Once issued, these certificates are usually valid for...
However, the role of ACLY in the fructose-driven NAFLD was recently questioned (Zhao et al., 2020), but as discussed further on, these results may not apply to NAFLD driven by long-term fructose consumption. However, it is also important to note that compared with glucose, fructose ...
After circSTK40 overexpression in both THESCs and primary hESCs and subsequent in vitro induction of decidualization for 2–6 days, the mRNA and protein levels of the decidualization markers prolactin (PRL) and insulin-like growth factor-binding protein 1 (IGFBP1) showed that the decidualization ...
To further verify the safety of artesunate for the treatment of obesity, we examined the clinical pathology parameters in normal and DIO mice treated with artesunate for 60 days using regular blood tests. Mice with long-term treatment with artesunate did not show any sign of clinical abnormalities...
In addition, FoxO1 has emerged as an important target of insulin and other growth factors in the myocardium16, and we have reported that FoxO1 is persistently activated in cardiac tissue from murine models of long-term diabetes17. Despite this, upstream regulators of FoxO1-dependent regulation of...