Her research interests are in the field of machine learning, object extraction, and segmentation/classification from point cloud data. Ravi Y. Peters is currently a post-doctoral researcher at the Department of Urbanism, Faculty of Architecture and the Built Environment, Delft University of Technology...
3: Our model that YAP facilitates GPCR transcription, while GPCR in turn facilitates the Hippo/YAP axis, is likely to be a general phenomenon in the cancer research field, which could reveal a broad phenomenon between Hippo signalling and GPCR. Similar content being viewed by others Background ...
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein. Nat. Cell Biol. 2, 423–427 (2000). Article CAS PubMed Google Scholar Cockman, M. E. et al. Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-...
Thus, showing that SELPi delayed the proliferation and invasion of GB cells in the presence of microglia and did not induce direct cell-killing. Since GBs are highly heterogeneous tumors, consisting of several molecular subtypes, we used three lenti-induced murine GB cells which represent the ...
2022) was used to obtain significant terms of gene ontology (GOTERM_BP_DIRECT) with an adjusted Fisher exact p-value < 0.05. KEGG enrichment analyses were carried out using clusterProfiler v3.14.3 (Yu et al. 2012), and the results of adjusted p-value < 0.05 were considered significant. ...
Sign in C5a-C5aR1 axis controls mitochondrial fission to promote podocyte injury in lupus nephritis Molecular Therapy Volume 32, Issue 5,1 May 2024, Pages 1540-1560 Purchase options CorporateFor R&D professionals working in corporate organizations. ...
The literature has shown the processes through which FAs exert a direct regulatory influence on gene expression and enzyme function [33]. In vitro,while PUFA (arachidonic acid (AA) > eicosapentaenoic acid (EPA) > docosahexaenoic acid (DHA) > linoleic acid (LA)) activates nuclear ...
Direct transformation of Zernike eye aberration coefficients between scaled, rotated, and/or displaced pupils. J Opt Soc Am A Opt Image Sci Vis. 2006;23(9):2061–6. Article PubMed Google Scholar Lundström L, Unsbo P. Transformation of Zernike coefficients: scaled, translated, and rotated...
“GOterm_direct” categories were used to search for GO (Gene Ontology) terms. The strength of enrichment for the annotation categories were identified with p-value (EASE score p-value; modified Fisher’s Exact Test 3), which reflect the threshold probability of biological significance. ...
In vitro studies revealed that Slc25a1 is a direct substrate of IRAKM. Furthermore, Slc25a1 phosphorylation induced by IRAKM kinase activity is required for its citrate transport activity and de novo fatty acid synthesis upon IL-1β stimulation. Moreover, IL-1β induces Pgc1a ...