The collagen receptor, discoidin domain receptor 2, functions in Gli1-positive skeletal progenitors and chondrocytes to control bone development Article Open access 09 February 2022 Introduction Fibrous tissues in the axial skeleton include the annulus fibrosus (AF) of the intervertebral disc (IVD),...
We did not previously address alterations in adhesion due to loss of Tgfbr2 in the axial skeleton. The profiling presented here suggests that this would be a logical avenue for future experiments to understand the mechanism of Tgfbr2 action in the development of the axial skeleton and ...
2]. Inflammation, bone and cartilage loss, and subsequent remodeling with new bone formation take place in the entheses, axial skeleton, and peripheral joints. Critically, axSpA encompasses two conditions:
Fig. 3: Microtubules immunolabeled for DNA-PAINT super-resolved in 3D using SIMPLER. a Microtubules in COS-7 cells. Left: top view. Right: magnified side-views along the numbered lines in the top view, together with the axial profile of the boxed areas. Top- and side-views have the sam...
Various vertebral formulae reflect both the requirements and the constraints associated with a skeleton that needs to accommodate protective, respiratory and locomotor functions (Romer, 1956, Woltering, 2012). The differentiation of initially similar somites into distinct type of vertebrae (i.e. ...