Ovarian cancer is the leading cause of death from gynecologic cancers. Each year over 21,000 cases are diagnosed and 15,000 deaths occur. Early diagnosis of ovarian cancer can help improve survival outcome; however, most cases of ovarian cancer are diagnosed in an advanced stage. An interim ...
Purpose: It is not clear that the published estimates of the breast and ovarian cancer penetrances of mutations in BRCA1 and BRCA2 can be used in genetic counseling in countries such as Spain, where the incidence of breast cancer in the general population is considerably lower, the prevalence...
These details included date of birth, date of or age at diagnosis of any breast or ovarian cancer, and age at death or age at last observation. Data on cancers other than breast or ovarian cancer were sometimes also available but were not used in the present analysis. Investigators were ...
Screening for ovarian cancer in asymptomatic women who are not known to have a high-risk hereditary cancer syndrome has no benefit and may lead to harm due to false positives, according to a new review conducted by the US Preventive Services Task Force (
This comparative effectiveness study assesses whether the health outcomes of White US citizens living in the 1% and 5% richest counties are better than
(a) Average of intensities for control and ovarian cancer patient datasetsTadayoshi, FushikiHironori, FujisawaShinto, Eguchi
The pattern of cancer risks was similar to those found in multiple-case families, but their absolute magnitudes were lower, particularly for BRCA2. The variation in risk by age at diagnosis of index case is consistent with the effects of other genes modifying cancer risk in carriers.Antoniou...
Objectives: Opportunistic bilateral oophorectomy (BO) is often considered in patients undergoing benign hysterectomy, but the degree to which BO reduces the incidence of ovarian cancer in this population remains unclear and is important for patient decision-making. Methods: We performed a population-...
Current data do not support ovarian cancer screening in women who are at average risk, with any screening regimen (moderate evidence). Transvaginal ultrasound (TVUS) is preferred as the initial test in evaluating women with postmenopausal bleeding (PMB) who are not on tamoxifen (moderate evidence...
What are the benefits and harms of ovarian cancer screening in average-risk women?doi:10.1097/EBP.0000000000000846Kimberly L CollinsMonica AgarwalElizabeth BrallierJose C Flores-RodarteEvidence-Based Practice