Monoclonal inhibitory anti-bevacizumab antibodies, use for PK assays to measure free drug, ADA surrogate positive control; bioanalysis and drug monitoring.
in negative controls provided. mRNAs with counts lower than the mean background +2 standard deviations were considered to be below the limits of detection. The nSolver (v.2.5) user interface (Nanostring) was used to operate the nCounter Advanced analysis module, which employs the R statistical...
In particular, the two different sequences of Fc fragments could be unambiguously distinguished. The results show that it is possible to obtain structurally dependent information at amino acid resolution of these important therapeutic agents. Crown Copyright (C) 2018 Published by Elsevier By. All ...