自身免疫性脑炎( Autoimmune encephalitis )是指与针对神经元细胞表面和突触蛋白的抗体相关的急性至亚急性、进行性脑部炎症,最常见的是抗N-甲基-D-天冬氨酸受体脑炎。它通常与潜在的恶性肿瘤相关,需要适当的筛查…
LIMBIC ENCEPHALITISObjectiveF-18 Fluorodeoxyglucose PET/CT (FDG-PET) is emerging as a useful imaging adjunct to MRI in the initial diagnostic evaluation of autoimmune encephalitis (AIE)-though presently it is not included in the diagnostic criteria.Materials and methodsIn this prospective study we ...
A number of immune-related conditions such as Behçet's disease, neurosarcoidosis, and Susac syndrome as well as infections can be associated with encephalitis and can have distinguishing MRI features. FDG-PET can often show abnormalities when brain MRI is normal, and CT and PET-CT are useful...
Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. 脑炎是一种严重的脑部炎症性疾病,可能有许多原因,而且诊断复杂。 Advances in autoimmune encephalitis research in the past 10 years have led to the identification of new syndromes an...
surface antigens and suggest an either paraneoplastic or nonparaneoplastic origin. MRI is abnormal in around 70% of patients with autoimmune limbic encephalitis and has a lower sensitivity than FDG-PET. The main indication to perform MRI remains the exclusion of a broad list of differential ...
Autoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central nervous system. While originally
Diagnostic Value of 18F-FDG PET/CT Versus MRI in the Setting of Antibody-Specific Autoimmune Encephalitis. Diagnostic value of 18 F-FDG PET/CT versus MRI in the setting of antibody- specific autoimmune encephalitis. J Nucl Med. 2017;58:1307-13... LB Solnes,KM Jones,SP Rowe,... - 《Jo...
Objective Brain 18F-FDG PET/CT is a useful diagnostic in evaluating patients with suspected autoimmune encephalitis (AE). Specific patterns of brain dysmetabolism have been reported in anti-NMDAR and anti-LGI1 AE, and the degree of dysmetabolism may correlate with clinical functional status.18FDG...
Autoimmune encephalitis associated with voltage-gated potassium channels-complex and leucine-rich glioma-inactivated 1 antibodies - a national cohort study. European journal of neurology. 2017;24:8.21. Park S, Choi H, Cheon GJ, Wook Kang K, lee DS. 18F-FDG PET/CT in anti-LGI1 encephalitis:...
Whole body FDG-PET is usually negative in patients with ovarian teratoma, while this test combined with CT of the chest are the best techniques to demonstrate lung cancer. The extent of tumour screening also depends on the type of antibody. For example, antibodies toAMPA-receptor associate to ...