13. New tools in the fight against autoimmune disease in the dog: the major histocompatibility complex Serum C4 concentrations and C4 allotypes were determined wherever possible on eight dogs with an autoimmune disorder characterized by antinuclear antibody (ANA) positivity, pyrexia, and seronegative ...
The prognosis for discoid lupus is usually good, but it is variable in the other diseases. Many dogs with VKH are euthanized due to blindness. Breeding affected dogs is not recommended. Currently, little information exists on the heritability of autoimmune skin diseases. Systemic lupus erythematosi...
49. B-cell, T-cell, myeloid-cell, mast-cell, and plasma-cell disorders are significant contributors to illness and mortality in domestic animals, especially in companion animals such as dogs and cats. These disorders include both autoimm... DM Goldenberg - US 被引量: 113发表: 2002年 Chines...
Chase, K., Sargan, D., Miller, K., Ostrander, E. A. & Lark, K. G. Understanding the genetics of autoimmune disease: two loci that regulate late onset Addison's disease in Portuguese Water Dogs.Int. J. Immunogenet.33, 179–184 (2006). ArticleCASPubMedPubMed CentralGoogle Scholar Hugh...
ObjectiveTo review the pathophysiology of thrombosis in hemolytic disease, and the efficacy of thromboprophylaxis in dogs with immune-mediated hemolytic an... L Kidd,N Mackman - 《Journal of Veterinary Emergency & Critical Care》 被引量: 28发表: 2013年 Monotherapy with Rituximab Induces Rapid Remis...
This species readily develops spontaneous diabetes when provided with a suitable environment, but the disorder is heterogeneous and phenotypic characterisation can be challenging. It therefore comes as no surprise that most experimental research in diabetes is performed in other animals, and tends to be...
(ILF2 and ILF3) as autoantigens in canine immune-mediated rheumatic disease. The ILF2 autoantibodies were discovered in a small, selected canine cohort through the use of human protein arrays; a method not previously described in dogs. Subsequently, ILF3 autoantibodies were also identified in ...
In theory, it would create little to no considerable indications during the immunological disorder treatment. Source: mcconnell.af.mil Curing Dogs With Autoimmune Disease The team will still do clinical trials to cure dogs with the condition due to autoimmunity before advancing to human tests even...
Human narcolepsy is most frequently a sporadic disorder with both genetic and environmental factors playing a role in its pathophysiology. Implication of the hypocretin system is well-established: as mutations in both canine and murine narcolepsies and as a consistent reduction in hypocretin neuron in...
Interestingly, several veterinary studies performed in dogs suffering wAIHA also identified VTE as an important source of mortality and suggested a causal relationship [12–14]. The aim of our study is to analyze the frequency, presentation and risk factors for VTE in patients with wAIHA. View ...