Because selective pressures change constantly, the immune system is highly adaptable. When that delicate balance is upset autoimmune disease, the consequence of disturbed homeostasis, may ensue. Different as they are in clinical presentation, the members of the autoimmune disease family share basic ...
Precision medicine in autoimmune disease 1Introduction Autoimmune diseasesare a set of diseases where immune system aberrancies lead totissue injury, morbidity and decreasedquality of life, increased mortality and high financial costs[1]. There are numerous autoimmune diseases includingtype 1 diabetes(T1DM...
Although the mechanisms underlying autoimmune disease are becoming clearer, our understanding of why, in some individuals, the immune system can be the cause of life-long, debilitating, and sometimes fatal disease remains incomplete. The incidence of autoimmune diseases is on the rise, and the needs...
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When the immune system turns against autoantigens, thus attacking its own tissues, the resulting condition is an autoimmune disease. Common autoimmune diseases include: • glomerulonephritis, which compromises the filtering ability of the kidney tubules • Graves' disease, which stimulates the ...
If you suffer from an autoimmune disease, you need to keep in mind that the term autoimmune disease doesnt refer to a single condition, but encompasses a variety of disorders that affect the immune system. An autoimmune disease like Addisons Disease is quite different from Autoimmune Thy...
Infections. Microorganisms like viruses and bacteria could set off changes that make your immune system attack itself. This may be more likely if you're genetically prone toimmune systemdisease. Certain risk factors raise your chances of getting an autoimmune disorder. Some common ones include: ...
Immune system disorder - Lupus, Autoimmune, Inflammation: Systemic lupus erythematosus (SLE) is a syndrome characterized by organ damage that results from the deposition of immune complexes. The immune complexes form when autoantibodies are made against
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Immune homeostasis does not rely exclusively on internal suppressive mechanisms of the immune system. Immunocompetence is dependent on, and adaptive and natural immune responses and inflammation are controlled by neuroendocrine regulatory mechanisms. By definition autoimmune disease develops upon the loss of...