Psoriasis, dysbiosis, autoimmune liver disease, and fecal microbiota transplantation may be the future research direction. Our research results can help researchers grasp the current status of ADs and gut microbiota research and find new research directions in the future.YouaoZhang· YongzhengPeng· Xu...
Faecal microbiota transplantation or inoculation with specific microbes in animal models of ADs support the hypothesis that alterations of gut microbiota influence autoimmune responses and disease outcome. Here, we describe the compositional and functional changes in the gut microbiota in patients with ...
autoimmune disease. With recent evidence highlighting the importance of the gastrointestinalmicroflorafor healthyimmune regulation, future studies are likely to further investigate the potential role of thegut microbiomein the initiation and progression of autoimmune diseases. Numerous questions remain regarding...
1). This pattern of relapsing and remitting is observed in many autoimmune disorders, reflecting the cyclic nature of autoimmune potentiation. Nonetheless, this conceptual framework suggests that antigen-specific immunotherapies can modify the immune system. Fig. 1: The pathogenesis of autoimmune disease...
7.1Systemic autoimmune disease induced epilepsy and the gut microbiota Epilepsy has been associated with varioussystemic autoimmune diseases(SAD) such as Chron's disease,systemic lupus erythematosus,Hashimoto's diseaseand others (Devinsky et al., 2013).Systemic autoimmune diseaseis essentially a group of...
However, gluten also provokes non-celiac autoimmune disorders, including Hashimoto’s disease and Sjögren’s syndrome, by activating inflammatory pathways, altering the composition of the gut microbiota, and increasing intestinal permeability. (22) Infections Though a lack of microbial exposure ...
Dos Santos PE, de Oliveira RC, Massaut KB et al (2024) Probiotics: Therapeutic strategy on the prevention and treatment of inflammatory diseases: Obesity, type 2 diabetes mellitus and celiac disease. Curr Nutr Food Sci 20:1112–1125. https://doi.org/10.2174/0115734013252358231016181809 Article CA...
The trillions of microbial symbionts normally hosted by mammals have important influences on the development and function of the immune system. We highlight recently discovered cellular and molecular mechanisms by which they impact autoimmune diseases —in particular, gut-distal disorders. Besides provoking...
compounds called ketone bodies. Ketone bodies provide energy for cells to burn and can also change the immune system. Working with a mouse model of MS, the researchers found that mice who produced more of a particular ketone body, called β-hydroxybutyrate (βHB), had less severe d...
A 2010 study alters the relationship between microfloras and disease greatly. The study found that metabolic profiles based on bacterial structural components and metabolites are disease-specific. In other words, the pathogens determine different microfloras mixtures. The mixture is almost a fingerprint ...