The device is intended to permit the delivery of medication over an extended period of time. An exemplary device for injecting medication may comprise: a housing; a cavity configured to accept a drug cartridge; a plunger configured to interact with the drug cartridge; at least one biasing ...
In addition, the mean Cmax value from the autoinjector was 314 ng/mL (c.v. = 18.7%, range 185 to 439 ng/mL) and 48.6 ng/mL (c.v. = 19.8%, range 29.4 to 69.7 ng/mL) for diazepam and desmethyldiazepam, respectively, while the syringe gave corresponding values of 287 ng/mL (c...
of connectivity and wearable devices in enhancing patient care. The BD Libertas™ Wearable Injector is a ready-to-use drug delivery system that supports the shift towards self-administration by enabling the subcutaneous delivery of large volumes of medication, ...
Considered the first-line treatment for the immediate treatment of anaphylaxis, epinephrine has been demonstrated to reduce or prevent hospitalization and reduce mortality, whereas delays in administering an epinephrine auto-...
to their anti-TNF therapy.41 For instance, a study in patients with ulcerative colitis showed that the majority preferred self-administration with golimumab autoinjector over a prefilled syringe.42 In multiple sclerosis, the adherence to medication has been focused on interferon beta-1a SC devices....
autoinjector use22; this can be justified in the context of treating anaphylaxis, but if used for mild reactions, the allergic individual may develop a reluctance to use epinephrine that impacts on the decision to treat subsequent reactions—including anaphylaxis—with appropriate rescue medication. ...
The study aimed to assess 52-week efficacy and safety of secukinumab self-administration by autoinjector in patients with active psoriatic arthritis (PsA) in the FUTURE 3 study ( ClinicalTrials.gov NCT01989468). Patients (≥ 18 years of age; N = 414)
Rather than spending your money on fuel injector cleaners, spend the money on a new fuel filter every few years. That's the single best thing you can do to protect your injectors. And if you have an older, fuel injected car that ran for a long time on gasoline without detergents, the...
A compression spring (141) is used to bias the plunger (111) to move towards the tip (15). The auto-injector (1) makes use of the compression spring (141) for both insertion of the needle into a body part and the injection of the drug into the body part. In this embodiment, a ...
An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syrin...