c,d, Heat maps of some representative signatures that are significantly different between primary and metastatic tumors in luminal/HER2E (n = 16 primary versus 29 metastatic tumors; c) and basal-like only subtypes (n = 10 primary versus 14 metastatic tumors; d). Significance of the...
Introduction Mitosis is a key step in the cell cycle, and it governs the production of new daughter cells from old ones. During this process, mitotic kinases, such as CDK1, Aurora-A, Aurora-B, and PLK1, are central players that drive entry into and progression through the division phase ...