A calculation method for carboplatin administration based on AUC is proposed. At present, the Calvert formula is used to calculate the carboplatin dose in clinical practice, and the creatinine clearance (CrCl) calculated by the Cockcroft-Gault equation is used to replace GFR. However, the Cockcroft...
A calculation method for carboplatin administration based on AUC is proposed. At present, the Calvert formula is used to calculate the carboplatin dose in clinical practice, and the creatinine clearance (CrCl) calculated by the Cockcroft-Gault equation is used to replace GFR. However, the Cockcroft...
[1]Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7:1748. [2] Egorin MJ, Van Echo DA, Olman EA, Whitacre MY, Forrest A, Aisner J. Prospective validation of a pharmacologically bas...
[1]Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7:1748. [2] Egorin MJ, Van Echo DA, Olman EA, Whitacre MY, Forrest A, Aisner J. Prospective validation of a pharmacologically bas...
For this reason, it can be important to measure the carboplatin AUC and subsequently adjust the dose to achieve a predefined target AUC. The use of limited sampling strategies enables relatively simple measurement and calculation of actual carboplatin AUCs. Methods : We studied the performance of a...
[1]Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7:1748. [2] Egorin MJ, Van Echo DA, Olman EA, Whitacre MY, Forrest A, Aisner J. Prospective validation of a pharmacologically bas...
[1]Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7:1748. [2] Egorin MJ, Van Echo DA, Olman EA, Whitacre ...
[1]Calvert AH, Newell DR, Gumbrell LA, et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7:1748. [2] Egorin MJ, Van Echo DA, Olman EA, Whitacre M...