Strange Bedfellows: Exploring the Relationship between R2P and Art. 4(h) of the AU Constitutive Act with Regard to Military InterventionAuthorizationUse of ForceAfrican UnionMilitary InterventionR2PThis essay revisits the relationship between Article 4(H) of the African Union Constitutive Act and the ...
Moreover, a number of FLT3 “activating” mutations have been identified, most notably the internal tandem duplication (ITD) found in the juxta-membrane domain (JM) and point mutations in the tyrosine kinase domain (TKD), both leading to constitutive activation of FLT3 kinase activity, and ...
ou l'exécution de tout autre acte frauduleux ou de toute autre ingérence ou tentative d'ingérence dans tout aspect de la procédure d'AUT peut être considérée comme constitutive d'une falsification ou d'une tentative de falsification au sens de l'article 2.5. Un Pilote ne doit pas ...
[0119] An inverse agonist able to block or inhibit a constitutive activity of an opioid receptor may also be used in certain embodiments. An inverse agonist may competitively or 25 non-competitively bind to an opioid receptor and/or a downstream signaling molecule to inhibit a receptor's functio...
25 Constitutive or inducible promoters as known in the art are contemplated by the invention. The promoters may be either naturally occurring promoters, or hybrid promoters that combine elements of more than one promoter. An expression construct may be present in a cell on an episome, such as ...
For example but not limitation, a constitutive promoter (e.g., an HSV-tk or pgk (phosphoglycerate kinase) promoter) or a cell-lineage specific transcriptional regulatory sequence (e.g., an CD4 or CD8 gene promoter/enhancer) may be operably linked to a protein encoding polynucleotide sequence ...
The theory of technological mediation aims to take technological artifacts seri- ously, recognizing the constitutive role they play in how we experience the world, act in it, and how we are constituted as (moral) subjects. Its quest for a compatible ethics has led it to Foucault's "care of...
Table 2a: Examples of constitutive promoters Gene Source Reference Actin McElroy et al, Plant Cell, 2: 163-171, 1990 HMGP WO 2004/070039 CAMV 35S Odell et al, Nature, 313: 810-812, 1985 WO 2010/012760 13 PCT/EP2009/059790 CaMV 19S Nilsson et al., Physiol. Plant. 100:456-462, ...
[0022] "Constitutive promoter" refers to a promoter that is able to express the gene that it controls in all or nearly all of the plant tissues during all or nearly all developmentalstages of the plant, thereby generating "constitutive expression" of the gene.[00231 "Co-suppression" and "...
[0128] In some embodiments, the vector includes one or mor promoters, such as but not limited to a constitutive, inducible, host-specific, and/or tissue-specific promoter. For example, commonly used promoters and enhancers are derived from human cytomegalovirus (CMV), Adenovirus 2, Simian Virus...