Atypical meningiomaRadiationRadiosurgerySkull baseWHO grade IIMeningiomas are the most common primary CNS tumor in adults, representing a third of brain lesions. Their clinical presentation varies greatly, ranging from asymptomatic incidental tumor to fatal tumor. The majority of meningiomas are benign, ...
Moreover, in contrast to patients with WHO grade I meningiomas whose lifespan is usually not abridged, survival in patients with atypical meningiomas is shortened to 11.9 years and to 3.3 years in patients after the diagnosis of anaplastic meningioma [2]. Treatment There is no established or ...
To evaluate if a better knowledge of the immune microenvironment of meningioma may help in planning treatments, we carried out a study on the tumor immune infiltrate (TII) looking for a role as a prognostic/predictive marker, suggesting tailored therapies. With this aim our study proposes the ...
The WHO grade and the extent of tumor resection assessed by the Simpson grading system are the most important predictors of recurrence. Atypical meningiomas, a grade 2 meningioma, which represent almost a fifth of all meningiomas, have a recurrence rate of around 50%. Currently, different ...
Figure 1. Secretory meningioma: WHO Grade 1 with eosinophilic secretions (pseudopsammoma bodies) and low mitotic rate [52]. The magnification is 100×. Figure 2. WHO Grade 3 (anaplastic) meningioma with high mitotic activity (>20 mitotic figures in 10 consecutive high-power fields) [25]. ...