5. Further skin biopsies taken from one newly developed papule and one old ulcerated plaque showed atypical lymphoid cell epidermotropism with formation of Pautrier`s microabscesses and perivascular and intravascular infiltration of atypical lymphocytes in the upper to middle dermis. ...
As one possibility, Tregs are an immunosuppressive sub-population of CD4+ lymphocytes that (1) modulate acquired immune responses and maintain tolerance to self-antigens, (2) have angiogenic properties, (3) can be isolated from peripheral blood, (4) are equally effective when allogenic to the ...
A bone marrow biopsy was done given the abnormal lymphocytes in peripheral smear, revealing budding yeast consistent with Histoplasma capsulatum. Histoplasma antigen was positive in urine and eventually blood and bone marrow grew H. capsulatum. Patient was started on amphotericin-B for diagnosis of ...
Adult T-cell leukaemia/lymphoma (ATLL) is a mature T-cell neoplasm of post-thymic lymphocytes aetiologically linked to the human T-cell lymphotropic virus, HTLV-I, and with a distinct geographical distribution. The disease manifests with... E Matutes - 《Journal of Clinical Pathology》 被引...
N. et al. A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells. J. Leukoc. Biol. 84, 1130–1140 (2008). Article CAS PubMed Google Scholar Décaillot, F. M....
Histopathologic study showed vasculitis with fibrinoid necrosis and granulation tissue with mixed cellular infiltrate of lymphocytes, mononuclear cells, neutrophils, mast cells (Fig 1, B and C ), and on immunofluorescence numerous T cells without B cells, with anti-C1q staining in proliferating ...
e, Flow cytometry analyis of total white blood cells (WBCs), neutrophils, lymphocytes, and neutrophil-to-lymphocytes ratio (NLR) (groups as in Fig. 8f). f, Average thrombogram of control conditions for tissue factor-triggered thrombin generation in FV and FVIII-deficient plasma (depleted), ...
T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein. tuberculosis, 2) intact recombinant 65-kDa hsp of Mycobacterium bovis/M. tuberculosis; or 3) tryptic fragments of the recombinant 65-kDa hsp. Strong CTL....
as subsets of lymphocytes, monocytes, or macrophages, proposed to express ACKR3, have also been shown to secrete and respond to opioid peptides78,79,80,81,82. The results of this study further strengthen the proposed crosstalk between the chemokine and the opioid systems but, by identifying a...
CD1a is a monomorphic antigen-presenting molecule on dendritic cells that presents lipids to αβ T cells. Whether CD1a represents a ligand for other immune receptors remains unknown. Here we use CD1a tetramers to show that CD1a is a ligand for Vδ1+ γ