atypical lymphocytesimmunophenotypeatypical lymphocytosislymphocyte subsetsBackgroundAtypical lymphocytosis is a common peripheral blood abnormality seen not only in Epstein-Barr virus (EBV)-associated acute infectious mononucleosis but also in other conditions, including other viral infections, cancer, immune ...
Heterophil antibody (HA) and Epstein-Barr virus (EBV) titers were performed on 45 children with ⩾5% atypical lymphocytes. None had a significant HA titer. Thirty-three were seronegative for EBV, and 11 had titers indicative of past infection. One child had an antibody pattern suggesting a...
We detected atypical lymphocytes in the blood of mice infected with both wt and UV-irradiated viruses. These atypical cells were similar in shape to those present in the blood of patients with IM induced by Epstein-Barr virus (EBV). Via Unscheduled DNA Synthesis (UDS), DNA synthesis was ...
In situ hybridization demonstrated a varying number of EBV-infected lymphocytes in the interfollicular area. The overall histomorphologic findings of the present six cases were similar to those of infectious mononucleosis (IM) in younger patients. However, the clinical findings were quite different from...
Her CSF demonstrated high protein: 0.69 g/L, glucose 3.5 mmol/L, polymorphs: 0 cells/uL, lymphocytes: 4 cells/uL, erythrocytes: 240cells/UL. Repeat CSF showed a negative polymerase chain reac- tion for viral studies, including herpes simplex virus (HSV), cytomegalovirus (CMV), ...
B. afzelii might even cause LNB with normal CSF cell counts [20]. The cause of granulocytic pleocytosis and the quick shift to predominantly lymphocytes in the CSF samples of the above mentioned patient remain unclear. Conclusion In conclusion, the presented case demonstrates the efficient use of...
Cutaneous γ/δ T-cell lymphoma (CGD-TCL) is a recent entity described in the newly revised World Health Organization-European Organization for Research and Treatment of Cancer classification of cutaneous lymphomas, and is characterized by the γ/δ T-cell receptor expression on atypical lymphocytes...
Post-mortem examination revealed both monoclonal and polyclonal proliferation of EBV-positive atypical T lymphocytes within different organs. Predominant infiltration of the nervous system and heart with extensive myocardial scarring accounted for the clinical symptoms. The remarkable features of this case ...
Flow cytometric analysis of his lymphocytes revealed a major subpopulation of atypical cells (20.3%) which were CD3+, fitted into the lymphocyte gate but showed a very low level of CD4 expression, comparable to that of monocytes. After short–time cell culture, the cells became ...
In situ hybridization demonstrated a varying number of EBV-infected lymphocytes in the interfollicular area. The overall histomorphologic findings of the present six cases were similar to those of infectious mononucleosis (IM) in younger patients. However, the clinical findings were quite different from...