–HPV-negative adenocarcinomas: HPV 阴性宫颈腺癌 MD,PhD, MBA, 俄亥俄州立大学韦克斯纳医学中心病理系副教授,住院医师培训项目联合主任,数字病理部副主任。具有解剖临床病理和细胞病理认证,临床和研究方向是乳腺/妇科病理,细胞病理和数字病理。在北京大学医学中心获得医学学位,在罗切斯特大学获得博士学位,在匹兹堡大学医...
HPV-positive AGC has a substantially higher positive predictive value for significant disease than ASC (61% vs historic 20%) and merits consideration in the triage of patients with atypical endocervical cells not otherwise specified. However, noncervical or other HPV-negative glandular neoplasia must...
The TBS 2001 introduced two important subgroups of ASC (atypical squamous cells) and AGC (atypical glandular cells) diagnostic categories. The authors aim was to classify the AGC cytological diagnoses according to the TBS 2001, carry out a follow up and retrospective cyto-histological comparison. ...
The subtype "suggestive of reactive" was a significant negative predictor of significant lesion (odds ratio = 0.09, 95% confidence interval 0.018, 0.482) in a logistic regression model controlling for age, menopausal status, and concurrent squamous diagnosis. Conclusion: Atypical glandular cells of ...
Among eight H-HPV-negative GLs, six (75%) had a diagnosis of lobular endocervical glandular hyperplasia (LEGH). Conclusion: The combination of CA-IX and HPV testing improved the diagnostic accuracy. The low rate of H-HPV positivity in the GLs was associated with coexisting LEGH independent ...
The diagnostic utility of these biomarkers was evaluated by the Gynecologic Oncology Group in Japanese women with a cytological diagnosis of atypical glandular cells. 机译:背景:高危型人乳头瘤病毒(H-HPV)感染与宫颈肿瘤相关,但在检测宫颈腺体病变(GLs)中的作用尚不清楚。碳酸酐酶IX(CA-IX)是一种缺氧...
Atypical glandular cellshuman papillomavirusPap testThe aim of this study is to analyze the correlation between clinically significant histologic results and HPV in women with AGC in pap test. Of the 311 women confirmed as AGC, 111 women (35.7%) was identified as positive for HPV. In the AGC...
Hr-HPV-positive AGC mainly occurs in cervical diseases, whereas hr-HPV-negative AGC is mainly related to en-dometrial lesions. Precancerous or malignant lesions were found in 36.43% (141/387) of AGC cases and were more commonly seen in AGC-FN than AGC-NOS (p < .001). The ...
Atypical glandular cellsObjectives: Early detection of endocervical adenocarcinoma is especially important for cancers that are human papillomavirus (HPV) negative. We investigated the clinicopathologic significance of yellow gastric-type mucin observed on Papanicolaou smears.Omori, MakikoKondo, TetsuoNakazawa,...
Atypical glandular cellsCervical cancerHPVSurePathThinPrepIntroductionThe interpretation of atypical glandular cells (AGCs) remains a major challenge in gynecologic cytopathology using liquid-based cytology (LBC) (ThinPrep and SurePath). The comparison of performance of detecting glandular abnormalities using...