中华心血管病杂志编辑委员会.转甲状腺素蛋白心脏淀粉样变诊断与治疗中国专家共识.中华心血管病杂志,2021,49(04):324-332. dermot phelan, et.al. relative apical sparing of longitudinal strain using two-dimensional speckle-tracking e...
15.Gillmore JD,et al. Nonbiopsy diagnosis of cardiac transthyretin amyloidosis[J]. Circulation,2016,133(24):2404-2412. 16.Brown EE,et al. Genetic testing improves identification of transthyretin amyloid (ATTR) subtype ...
[4]Advances in the treatment of hereditary transthyretin amyloidosis: A review(DOI: 10.1002/brb3.1371) [5]MUCHTAR E, et al. Restrictive cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy[J]. Circ Res, 2017, 121(7): 819-837. [6]中华医学会心血管病学分会心...
[21] Rozenbaum, Mark H., et al. "Impact of delayed diagnosis and misdiagnosis for patients with transthyretin amyloid cardiomyopathy (ATTR-CM): a targeted literature review." Cardiology and therapy 10.1 (2021): 141-159.[22] Lamb, Yvette N., and Emma D. Deeks. "Tafamidis: a review in ...
What tests are needed to confirm the diagnosis? How can we figure out if ATTR-CM is hereditary? What are my treatment options? What are the side effects? What are the signs of an emergency? Are there any clinical trials or new therapies I should know about? Other questions to consider ...
[8] Hayashi, Yuya, and Hirofumi Jono. "Recent advances in oligonucleotide-based therapy for transthyretin amyloidosis: clinical impact and future prospects." Biological and Pharmaceutical Bulletin 41.12 (2018): 1737-1744. [9] Kapoor, Mahima,et al. "Clinical presentation, diagnosis and treatment of ...
To help improve the early suspicion and diagnosis of ATTR-CM, we are supporting AI technology innovation in hospitals globally. This is reflected in ongoing partnership initiatives in the US, Germany, Japan, and Canada that leverage specialized AI algorithms. Through these initiatives, AI tools usin...
METHODS. In this retrospective, non-interventional, observational study using a claims database (dataset period: April 1, 2014–August 31, 2021), adult patients with a diagnosis of ATTR-CM or prescription for tafamidis 80 mg were included. The index date was defined as the first date of ...
*Also known as transthyretin amyloid cardiomyopathy (ATTR-CM). Early, accurate diagnosis of ATTR cardiac amyloidosis can benefit patient care and may lead to improved outcomes.3,4 Learn more about what to look for to raise suspicion of ATTR cardiac amyloidosis and how to diagnose the disease....
Transthyretin (TTR), also called prealbumin, plays a role in processes vital to human health. TTR destabilization is the root cause of ATTR-CM.