In this study, we used telomerase-positive cancer cells (HTC75) to discover the mechanism of the telomerase- ALT switch by inducing telomere-specific DNA damage, alpha-thalassemia X-linked syndrome protein (ATRX) knockdown and deletion of death associated protein (DAXX). Surprisingly, two ...
In this study, we used telomerase-positive cancer cells (HTC75) to discover the mechanism of the telomerase- ALT switch by inducing telomere-specific DNA damage, alpha-thalassemia X-linked syndrome protein (ATRX) knockdown and deletion of death associated protein (DAXX). Surprisingly, two ...