Accordingly, the Canadian Trial of Atrial Fibrillation was designed as a large randomized comparison of the relative efficacy and safety of low-dose amiodarone vs standard therapy (propafenone or sotalol) for maintenance of sinus rhythm in patients with atrial fibrillation. After a mean follow-up of...
importance for these patients. Treatment with AV node-blocking medications such as verapamil or digoxin can facilitate rapid conduction over the accessory pathway and result in ventricular fibrillation. When intravenous pharmacologic therapy is required, the drug of choice is procainamide or amiodarone. ...
Drugs used in treating atrial fibrillation often have important side effects. Many patients discontinue them because they cannot tolerate these side effects. For example: Amiodarone commonly is used to treat atrial fibrillation because it is less proarrhythmic, and has been shown to maintain a normal...
quinidine concentrations for conversion from atrial fibrillation to sinus rhythm are 2 to 5 μg/ml. One should base subsequent quinidine sulfate administration on the most recent plasma concentration. The mean quinidine elimination half-life after an oral 10-g dose is 6.65 hours.257,639Thus after...
Atrial fibrillation is a supraventricular tachyarrhythmia and the most common kind. It is caused by rapid, uncontrolled atrial contractions and uncoordinated ventricular responses.
Beta-blockers, non-dihydropyridine calcium channel blockers, digoxin, and intravenous amiodarone are contraindicated in these patients; flecainide or amiodarone can be used instead.[1, 76] Anticoagulation One of the most important considerations in the acute management of atrial fibrillation is the ...
Atrial Fibrillation Medications With AFib, abnormal electrical signals make your heart quiver or flutter. It can also beat too fast. This sensation is sometimes called palpitations. AFib prevents blood from flowing normally from your heart's upper chambers (called the atria) to the lower ones (the...
Amiodarone for Atrial Fibrillation West China Medical Journal | 2010, 25(1): 117-118 Article Views:3388 PDF Downloads:0 Cited by:0 Authors: XIE Yingwei Keywords: 胺碘酮; 心房颤动; 治疗 Export PDF Favorites Scan Get Citation Shared Abstract Figures/Tables References Cited by 目的:...
Amiodarone has effects within all four Vaughn Williams classes, so it has arrhythmia-promoting and suppressing potential. It inhibits INa, beta receptors, IKr, IKs, Ito, IK1, and ICa-L [174], but the effects of the drug apparently evolve over time, with class I and IV effects...
Atrial fibrillation (AFib) is a problem with your heart's electrical activity. With AFib, your heart quivers, beats irregularly, or skips beats. It can't pump blood through its chambers and out to your body as well as it should. Sometimes, blood can pool in the heart and form clots, ...