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ATM = zeros(1,n); % Initialize level of ATM/ATR activation ATR = zeros(1,n); % AT_tot = par(end); % total ATM or ATR is always last parameter % max_activation = AT_tot*tmax; % The maximum possible activation level; everything is always on s = 0; for i=1:n % run ODEs ...
S Rimmer,I Soutar,L Swanson - 《Polymer International》 被引量: 81发表: 2009年 Temperature dependent activity and structure of adsorbed proteins on plasma polymerized N-isopropyl acrylamide Thorough studies of protein interactions with stimulus responsive polymers are necessary to provide a better unders...
DNA damage, especially DNA double strand breaks (DSBs) and replication stress, activates a complex post-translational network termed DNA damage response (DDR). Our review focuses on three PI3-kinase related protein kinases—ATM, ATR and DNA-PKcs, which s
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Error bars represent s.d. (n ¼ 3), ANOVA P value of o0.0001, results are representative of triplicate biological experiments. (l). Western blot of Arid1a protein expression in mouse ES Arid1a isogenic cells. observations using ATRi, HCT116 ARID1A isogenic cells had a ARID1A À / ...
doi:10.1016/j.annder.2011.01.046Z. Lamam BennaniL. BoussofaraM. DenguezliN. GharianiR. NouiraElsevier Masson SASAnnales De Dermatologie Et De Venereologie
We next used Smurf1-3A, a mutant with Thr145, Thr161 and Thr682 mutated to alanines, to perform the in vitro phosphorylation assay. As expected, point NATURE COMMUNICATIONS | 5:4901 | DOI: 10.1038/ncomms5901 | www.nature.com/naturecommunications & 2014 Macmillan Publishers Limited. All ...
Error bars represent S.D.s. An obvious complication in creating an RPA-based ATR repressor is that tethering of WT RPA to telomeres would permanently recruit and likely activate the ATR kinase. The interaction of RPA70 with the ATRIP/ATR complex is mediated by its fourth (N-terminal) OB-...