The plasma membrane H+-ATPase gene family in Arabidopsis: genomic sequence of AHA10 which is expressed primarily in developing seeds The plasma membrane H+-ATPases in Arabidopsis thaliana represent the largest family of cation translocating P-type ATPases identified in plants or animals... JF ...
+-ATPase Reconstituted into Nanodiscs Is a Monomer.]]>doi:10.1074/jbc.M112.446948Plasma membrane H+-ATPases form a subfamily of P-type ATPases responsible for pumping protons out of cells and are essential for establishing and maintaining the crucial trans-membrane proton gradient in plants and...
氢ATP酶(H+-ATPase;EC3.6.3.6),又称为质子或氢离子转位ATP酶(Proton-Translocating ATPases),在生物能量传导过程中起着重要作用。其分成三类:质膜型(plasma membrane type或P型)、真细菌型(eubacterial type或F型)和囊/液泡型(vacuolar type或V型)。质膜型存在于植物、酵母和胃酸分泌型囊泡的质膜上,约100kd...
Luo S, Rohloff P, Cox J, Uyemura SA and Docampo R (2004) Trypanosoma brucei plasma membrane-type Ca(2+)-ATPase 1 (TbPMC1) and 2 (TbPMC2) genes encode functional Ca(2+)-ATPases localized to the acidocalcisomes and plasma membrane, and essential for Ca(2+) homeostasis and growth....
2 Plasma membrane-localized RAC1 is required for RAS-induced macropinocytosis. a, b, Effect of V1A expression on RAC1 activity. a, Immunoblots of RAC1 wild type and RAC1(L61) activity (GST–PBD, pull-down of GFP–RAC1–GTP; vinculin loading control) with or without V1A knockdown in...
Fig. 1: Plasma membrane (PM) H+-ATPase regulates ammonium (NH4+) uptake in rice. a15NH4+absorption rate in wild-type (WT) rice. To determine15NH4+absorption rates, rice seedlings were incubated in 2 mM15NH4+solution with 5 μM fusicoccin (FC) for 30 min under dark or illuminat...
V-ATPase overexpression in cancer is also correlated to multidrug resistance, what can be due to the ion-trapping phenomenon or to the altered pH of the microenvironment, that is critical for theanticanceragent action[71]. Besides being expressed at the plasma membrane, V-ATPases are also pres...
Martínez-Zaguilán, R., Lynch, R., Martinez, G., and Gillies, R. (1993) Vacuolar-type H+ATPase are functionally expressed in plasma membrane of human tumor cells.Am. J. Physiol.265, C1015-C1029. PubMedGoogle Scholar Griffiths, J. R. (1991) Are cancer cells acidic?Br. J. Cancer...
Addition of 10 μM vanadate, an inhibitor of plasma membrane H +-ATPase (P-ATPase), to the wild type strains also increased the inactivation ratio. These results clearly show that V- and P-ATPases contribute to the tolerance against HPCT in S. cerevisiae by accumulating excess H + from...
Binding of 14-3-3 Protein to the Plasma Membrane H+-ATPase AHA2 Involves the Three C-terminal Residues Tyr946-Thr-Val and Requires Phosphorylation of Thr947 14-3-3 proteins play a regulatory role in a diverse array of cellular functions such as apoptosis, regulation of the cell cycle, and...