Gene Typeprotein_coding Uniprot IDO14983 Pathway/Libraryothers Gene SummaryThis gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation...
Gene SummaryThis gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lum...
Research studies have shown that mutations in the ATP2A1 gene cause an autosomal recessive muscle disorder known as Brody myopathy, which is characterized by muscle cramping and impaired muscle relaxation associated with exercise (1-3). Hovnanian, A. (2007) Subcell Biochem 45, 337-63. ...
Gene Symbol ATP2A1 Gene ID (NCBI) 487 RRID AB_3671770 Conjugate Unconjugated Form Liquid Purification Method Protein A purfication UNIPROT ID O14983 Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Storage Conditions Store at -20°C. Stable for one year after shipment. ...
Pan Y, Zvaritch E, Tupling AR, Rice WJ, de Leon S, Rudnicki M, McKerlie C, Banwell BL, MacLennan DH: Targeted disruption of the ATP2A1 gene encoding the sarco(endo)plasmic reticulum Ca2烯 ATPase isoform 1 (SERCA1) impairs diaphragm function and is lethal in neonatal mice. J Biol ...
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. Storage Instruction Store at -80°C. Aliquot to avoid repeated freezing and thawing. Note Best use within three months from the date of receipt of this protein. Applications Gene Info — ATP2A1 Interactomes Pathways...
提供的ATP2A1人源重组蛋白(P01)产品为带有GST标签的人源ATP2A1全长序列重组蛋白,其对应的GeneID号为487。 产品描述 与其它公司提供的重组蛋白不同,该ATP2A1人源全长重组蛋白(P01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,...
背景资料 SERCA1,also called ATP2A1,is an enzyme that in humans is encoded by the ATP2A1 gene.This gene encodes one of the SERCA Ca(2+)-ATPases,which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells.The SERCA1 gene is mapped to 16p11.2.This en...
该ATP2A1 Polyclonal Antibody. This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarco...
reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in two transcript variants encoding different ...