These results suggest that adenosine polyphosphopyridoxals bind to the ATP-binding site(s) in phosphorylase kinase. When phosphorylase kinase was incubated with adenosine triphosphopyridoxal in the presence of Ca2+ and Mg2+, incorporation of the label into alpha, beta, and gamma subunits was ...
The interaction of ATP with the active site of hexokinase is unknown since the crystal structure of the hexokinase-ATP complex is unavailable. It was found that the ATP binding site of brain hexokinase is homologous to that of actin, heat shock protein hsc70, and glycerol kinase. On the basi...
A., Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase. Biochem. J. 2011, 440, 85-93.Pflug A, de Oliveira TM, Bossemeyer D, Engh RA (2011) Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase . Biochem J 440 :85–93....
(1989): Hypothetical structure of the ATP-binding site of (Na++K+)-ATPase. Gen. Physiol. Biophys. 8, 283--286Breier A, Turi Nagy L, Ziegelh6... A Breier,L Turi-Nagy,A Ziegelhffer,... - 《General Physiology & Biophysics》 被引量: 9发表: 1989年 Structure-based assignment of the ...
KLINGBEIL C K ET AL: " A Basic Residue, Lys 782, Composes Part of the ATP-Binding Site on the Epidermal Growth Factor Receptor Tyrosine Kinase " ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, NEW YORK, US, US, vol. 363, no. 1, 1 March 1999 (1999-03-01), pages 27-32, XP004635450 ...
The results obtained with the Na+,K+-, H+,K+- and sarcoplasmic reticulum Ca2+-ATPases indicate that the ATP binding site, to which eosin is known to bind, is significantly more polar in the case of the Na+,K+- and H+,K+-ATPases compared to the Ca2+-ATPase. This result was ...
This lysine has been shown to be part of a conserved ATP-binding site in both the catalytic subunit of the cAMP-dependent protein kinase and p60v-src. We wished to determine whether this lysine is required for the transforming activity of p37mos. Two site-specific mutations were therefore ...
Phenylglyoxal (PGO) was used as a reagent for chemical modification of the ATP-binding site of Ca2+-transporting ATPase of rabbit skeletal muscle sarcoplasmic reticulum (SR-ATPase). When 1 mM PGO was reacted with SR-ATPase at 30掳C at pH 8.5, PGO was bound to the ATPase molecule in two...
The potential location of the second ATP binding site was deduced from sequence comparisons and molecular visualisation in conjunction to data obtained from biochemical analysis. 展开 关键词: Azathioprine Binding Sites L Peptides Ligases 硫唑嘌呤 结合部位 肽类 连接酶类 ...
The recently proposed DoGSite method investigated the concept of subpockets and the difference of Gaussian approach (DoG) is found to be able to improve the prediction rates of protein active sites [35]. Except for the efforts to find the discriminative features of interaction sites and their ...