In the present work, we describe a modification of the luciferase/luciferin technique that allows rapid continous measurement of the ATP synthesis rate with a high time resolution at physiological (millimolar range) concentrations of ATP. The principle is based on the properties of a modified ATP, ...
100 Years of Biochemistry and Molecular Biology ATP Synthesis and the Binding Change Mechanism : the Work of Paul D . BoyerTriphosphatase, Mitochondrial Adenosine
- 《Journal of Experimental Biology》 被引量: 0发表: 2024年 ATP Synthase Subunit a Supports Permeability Transition in Yeast Lacking Dimerization Subunits and Modulates yPTP Conductance Background/Aims: Mitochondrial ATP synthase, in addition to being involved in ATP synthesis, is involved in ...
- 《Journal of Membrane Biology》 被引量: 179发表: 1992年 Biotinyl-5'-adenylate synthesis catalyzed by Escherichia coli repressor of biotin biosynthesis Several methods employed for determination of the thermodynamic stability of the BirA-adenylate complex are presented. The fractional activity of a ...
Thus, instead of being hypermetabolic, as commonly assumed, solid tumours generally produce ATP at a slower than normal rate. In mouse pancreatic cancer, this is accommodated by the downregulation of protein synthesis, one of this tissue’s major energy costs. We propose that, as solid tumours...
[1, 5, 6]. F-ATPase is commonly assumed to be respiratory chain complex V in the inner membrane of mitochondria; this complex consists of a transmembrane proton transport domain, F0, and an ATP synthesis catalytic domain, F1 [7]. The key role of F-ATPase is transferring protons from ...
Sherer et al., in 2011, reported the synthesis of substituted pyrrolamide based analogues from substituted pyrrole derivatives as Mtb GyrB inhibitors. The synthesized compounds were evaluated for both antibacterial and enzymatic activity. The SAR (Structure activity relationship) analysis of the synthesize...
Synthesis of interleukin-5 by activated eosinophils in patients with eosinophilic heart diseases. SHAPE TRANSFORMATIONEosinophilic endomyocardial disease represents a major evolutive risk in chronic eosinophilia-associated disorders. Eosinophil granule proteins ... P Desreumaux,A Janin,S Dubucquoi,... - 《...
Mitochondria serve a crucial role in cell growth and proliferation by supporting both ATP synthesis and the production of macromolecular precursors. Whereas oxidative phosphorylation (OXPHOS) depends mainly on the oxidation of intermediates from the tricarboxylic acid cycle, the mitochondrial production of ...
Chloroplast ATP synthase (CF1FO) from higher plants has a unique redox switch that serves to modulate the ATP synthesis activity4,6,7. The CF1FO enzyme actively synthesizes ATP in the reduced state, whereas the oxidized form has a low activity6,8. At sunrise, in the thylakoid membrane,...