"Nonlinear coupling between cerebral blood flow, oxygen consumption, and ATP production in human visual cortex." Proceedings of the National Academy of Sciences of the United States of America 107(18): 8446-8451.Lin A-L, Fox PT, Hardies J, Duong TQ, Gao J-H. Nonlinear...
As expected, glycolysis flux is increased in tumours compared with healthy tissues (the Warburg effect2,3), but this increase is insufficient to compensate for low TCA flux in terms of ATP production. Thus, instead of being hypermetabolic, as commonly assumed, solid tumours generally produce ATP...
Proton-translocating respiratory complexes assemble into supercomplexes that are proposed to increase the efficiency of energy conversion and limit the production of harmful reactive oxygen species during aerobic cellular respiration. Cytochrome bc complexes and cytochrome aa3 oxidases are major drivers of t...
ATP production was increased in the host cells after VV infection. Moreover, 4.5 μM oligomycin, an inhibitor of ATP production, reduced the ATP level 13 hr after virus infection to that of mock-infected cells and inhibited viral protein expression and virus production, suggesting that increased...
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Thus, the molecule is essential for coupled respiration leading to ATP production in mitochondria. Mice have three paralogous ANT genes, Ant1, Ant2 and Ant4 (ref. 5). Ant1 is highly expressed in skeletal and cardiac muscle, and its disruption leads to exercise intolerance and cardiomyopathy6...
Trypanosoma brucei is a parasitic protist responsible for sleeping sickness in humans. The procyclic form of this parasite, transmitted by tsetse flies, is... V Coustou,S Besteiro,M Biran,... - 《Journal of Biological Chemistry》 被引量: 152发表: 2003年 Cloning, Heterologous Expression, and ...
Mimicking diabetic phenotypes by exposure to various glucose levels (0, 5, and 25 mM) resulted in immediate adjustments of glycolytic and mitochondrial activity that aimed to maintain intracellular ATP. We conclude that ATP deficits by mitochondrial failure are compensated by glycolytic ATP production,...
Baljit S. Khakh, Geoffrey Burnstock, “The Double Life of ATP in Humans”, Scientific American, SCIENTIFIC AMERICAN, a Division of Springer Nature America, Inc., Dec 1, 2009, viewed on February 12, 2023. Barclay CJ. Energetics of contraction. Compr Physiol. 2015 Apr;5(2):961-95. doi...
Name the metabolic pathway wherein glucose converts to pyruvic acid. Indicate which energy system is being described. Produces over 30 molecules of ATP per glucose: A. Glycolysis B. Aerobic Respiration Which of the following metabolic pathways...