分析: 由题干和图可知,细胞膜上存在着P2X、P2Y和P1受体,而ATP与P2X和P2Y受体特异性结合,直接引起神经纤维发生电位变化,则ATP可以在神经细胞之间传递信息.ATP全名叫做三磷酸腺苷,结构简式A﹣P~P~P,其中A代表腺苷,P代表磷酸基团,~代表高能磷酸键;细胞中ATP和ADP的含量不多,是不断的相互转化,维持动态平衡的;...
James G, Butt AM: P2X and P2Y purinoreceptors mediate ATP-evoked calcium signalling in optic nerve glia in situ. Cell Calcium 2001, 30:251-259.James G, Butt AM (2001) P2X and P2Y purinoreceptors mediate ATP-evoked calcium signalling in optic nerve glia in situ. Cell Calcium 30(4):...
3最新研究证实ATP既是“能量通货”,也可作为神经细胞间信息传递中的一种信号分子,其作为信号分子的作用机理如图所示,请分析回答:释放ATP的细胞囊泡酶ADP AMP ATP P2Y受体P1受体P2X受体接受ATP信号的细胞(1)在下列生物体的生命活动中,不直接依赖于ATP水解的是A.胃蛋白酶的合成B.细胞的生长C.骨髓肌的收缩D.红细...
Leukocytes of both the innate, adaptive immune and central nervous system express a repertoire of cell surface receptors for ATP (P2X and P2Y receptors) and its metabolites. ATP acts as a damage-associated molecule pattern (DAMP) released by injured or dying cells. Detection of released ATP by...
functions. Furthermore, this study illuminates novel cellular and systemic features of P2X-type ligand-gated ion channels for deciphering the evolution of neurotransmitters. Similar content being viewed by others Introduction In addition to being the critical energy storage for every cell, ATP acts as...
【题目】分析下列生物放ATP的细学实验:(1)下表是某同学用不型神经递同浓度的蔗糖溶液、 在n2AMP不同时间下,记录一个P2Y受视野中的某植物表皮细P受P2X受体收ATP号的细胞胞发生质壁分离的数量(已知视野中共有细胞40个).引起50%左右的细胞发生初始质壁分离的浓度,称之为细胞液的等渗浓度.该植物表皮细胞液的...
ATP might also contribute to cancer drug resistance from outside of the cell through P2X and P2Y purinergic receptor signaling. For example, lymphocytes release, when stimulated, large amounts of ATP into the extracellular space serving as a messenger in cellular interactions. The ATP released ...
Less known is that this molecule has a variety of important signaling func- tions: it activates a variety of specific metabotropic (P2Y) and ionotropic (P2X) receptors in neuronal and non-neu- ronal cell membranes. So, a wide variety of signaling func- tions well fits the ubiquitous ...
The bladder urothelium is more than just a barrier. When the bladder is distended, the urothelium functions as a sensor to initiate the voiding reflex, during which it releases ATP via multiple mechanisms. However, the mechanisms underlying this ATP rele
there is a significant body of information indicating that inhibition of P2X3receptors may be useful for relieving inflammatory and neuropathic pain. More recently, data have begun to emerge implicating P2X4, P2X7and P2Y receptors in aspects of pain transmission. Both P1 and P2 receptors may repres...