In cats, histopathologic features of atopy-like dermatitis include perivascular to diffuse dermal infiltration of T lymphocytes, activated antigen presenting cells, eosinophils, macrophages and high numbers of mast cells [35]. A significant increase of CD4+ T cells, IL-4 and CD1a+ dentritic cell...
Objective--To evaluate the efficacy of the probiotic Lactobacillus rhamnosus strain GG for the alleviation or prevention of clinical signs of atopic dermatitis (AD) in genetically predisposed dogs. Animals--2 adult Beagles with severe AD and 16 puppies. Procedures--The 2 adult Beagles were bred ...
Current knowledge regarding the role of Treg cells in the initiation of allergic disease is limited for both people and dogs. Objectives: To explore the role of circulating Treg cells and their possible influencing factors, on the development of atopic dermatitis (AD). Methods and materials: This...
Canine atopic dermatitis (CAD) is a prevalent inflammatory skin disease of dogs worldwide. Certain breeds such as the West Highland White Terriers (WHWT) are predisposed to suffer from CAD. Microbial dysbiosis is known to play a significant role in the pathogenesis of the disease, which is ...