A 72 year-old woman developed diffuse pruritus 14 months prior to presentation. She developed worsening eczematous erythematous papules throughout her body with excoriations, which waxed and waned. Pruritus was intermittently controlled with hydroxyzine, a potent topical corticosteroid, and over-the-...
Atopic Dermatitis (AD) is a heterogeneous disorder with a wide spectrum of clinical signs, symptoms, severity and clinical course. Consequently, there is no single tool that comprehensively assesses all aspects of the disease. There are presently >60 measures that have been used to assess the sev...
Late-breaking Oral Presentation Efficacy and Safety of a Highly Selective Oral TYK2/JAK1Inhibitor, ICP-332, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II, Randomized, Placebo-Controlled Trial Abstract Number: 56157 This is a four-week multi-center (25 centers), randomized, d...
Atopic dermatitis, commonly known as eczema, is a chronic inflammatory dermatosis that can affect individuals from infancy to adulthood. Also referred to as "the itch that rashes", atopic dermatitis is classically associated with significant pruritus that is accompanied by characteristic cutaneous and ...
Atopic dermatitis is a chronic inflammatory disease, usually associated with a personal or family history of atopic diseases such as AD, allergic rhinitis or asthma that most commonly arise in childhood and present with elevated IgE serum in up to 85% of patients. The severity of AD is based ...
house dust mitecytokinesBackground: Atopic dermatitis (AD) is a common chronic inflammatory skin disease. To understand AD, there have been many trials establishing AD animal models. Although various trials to establish AD animal models have been existed, even the mechanisms of AD in animal models...
British Journal of DermatologyKerr A, Dawe RS, Nathwani D, et al. Presentation of leishmaniasis (Leishmania infantum) in the skin of a patient with severe atopic dermatitis. Br J Dermatol 2009;161:202-3.Kerr A, Dawe RS, Nathwani D, Evans AT, Ferguson J. Presentation of leishmaniasis (...
While a growing body of research is uncovering the aetiology and effective treatments for allergy, research that assess the broader ethical implications of this disease is lacking significantly. This article will demonstrate both the paucity of academic research concerning ethical implications in allergy ...
Adult-onset atopic dermatitisAtopic dermatitis (AD) is a chronic skin condition that can manifest in childhood and persist into adulthood or can present de novo in adults. The clinical presentation of adults with AD may differ among those with pediatric-onset versus adult-onset disease and ...
Autoallergy: a pathogenetic factor in atopic dermatitis? J Allergy Clin Immunol 2000; 105: 432-437.Stingl G (2001) IgE-mediated, Fc (epsilon) RI-dependent allergen presentation: a pathogenetic factor in atopic dermatitis? J Am Acad Dermatol 45: S 17–S 20...