Comorbidities of atopic dermatitis Emerging research has shown that AD is associated with numerous medical and mental health comorbidities in adults. However, much of the research into these comorbidities is nascent. There is strong evidence to support the association of AD with atopic disease, as we...
Atopic dermatitis (AD) is a chronic, pruritic inflammatory skin disease of unknown origin that usually starts in early infancy, but also affects a substantial number of adults. Left untreated, the barrier function of the skin is compromised, increasing susceptibility to dehydration and infection. It...
T-helper 2 cells are central to mediating atopic eczema inflammation and specific targeted interventions are progressing well in clinical trials. Further developments in our understanding of disease pathogenesis, including the role of thymic stromal lymphopoeitin, and recently discovered subsets of immuno...
Long-Term Safety of Dupilumab in Adults with Moderate to Severe Atopic Dermatitis Lauren Buchanan, MA, Managing Editor November 3rd 2023 The results from this 5-year open-label extension trial affirm the safety of dupilumab in adults with moderate to severe AD. ...
Atopic dermatitis (AD) is an inflammatory skin disease that typically manifests for the first time in early childhood. Although it often improves during adolescence, it may also become a chronic co...
Upadacitinib(Rinvoq) appears effective foratopic dermatitis(AD) in adolescents and adults, with no unexpected safety concerns, according to two new duplicate phase 3 trials. The Measure Up 1 and Measure Up 2 trials, each pitting both 15-mg and 30-mg doses of upadacitinib monotherapy against...
Atopic Dermatitis Atopic dermatitis is a common eczematous condition related to a family history of hay fever, allergic rhinitis, asthma, dry skin, and increased levels of immunoglobulin (Ig) E. It can occur at any age but is most prevalent in infants to young adults. The tendency for the ...
The problem is adult clinic trials for medications like these usually only enroll adults up to age 65. RELATED: Diagnosing adult-onset atopic dermatitis MORE RESEARCH NEEDED Many studies and clinical guidelines addressing atopic dermatitis don’t include the elderly or distinguish adults 60 years and...
This quiz, the first in 4 part series, focuses on pivotal data from the INTEGUMENT trials in atopic dermatitis. Safety Protocols With JAK Inhibitors ByBrad P. Glick, DO, MPH Zed Zha, MD, FAAFP March 24th 2025 Panelists discuss how the Measure Up 1 and 2 studies (Simpson 2022) showed ...
Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life (QoL) of affected individuals as well as their families. Although the pathogenesis of the disorder is not yet completely understood, it appears to