In this study, we combined seven single-cell transcriptomic datasets, comprising more than a million cells from one hundred and three donors, to create a unified atlas of human peripheral blood mononuclear cells (PBMC) from both young and old individuals. Using a consistent set of marker genes ...
including the Human Cell Atlas, are already revealing valuable biological insights, and how they are poised to provide even greater benefits in the coming years. In particular, we discuss cell atlases as censuses of cells; as 3D maps of cells in the body, across modalities and scales; as map...
The specialisation of mammalian cells in time and space requires genes associated with specific pathways and functions to be co-ordinately expressed. Here we have combined a large number of publically available microarray datasets derived from human prim
bloodprogenitor ‘Earlyresponder’ immunecells Fishembryo PathogenicTcells inMSmodel Musclecell differentiation CSCspectrum inglioma GSCBMP4 scRNA-Seq Insitu Thesequencer:amicroscopeforthe21 st century TheHumanCellAtlasProject What?Acensusofallcells •Types •States •Transitions •Location Why?Arefere...
The team analyzed almost a half-million individual cells to build the most extensive cell atlas of the human heart to date. The atlas shows the huge diversity of cells and reveals heart muscle cell types, cardiac protective immune cells, and an intricate network of blood vessels. Using state-...
What common pathway was identified between Single Cell Rna Sequencing (scRNA-seq) data of old versus young human skin and RNA-seq data from fibroblasts with HES1 knockdown? What types of skin cells showed decreased density during aging?
scRNA-Seq analysis of 21,343 cells from four adult human corneas and adjacent conjunctivas revealed the presence of 21 cell clusters, representing the progenitor and differentiated cells in all layers of cornea and conjunctiva as well as immune cells, melanocytes, fibroblasts, and blood/lymphatic ...
Fine structure of arterial smooth muscle cells cultured in the presence of whole blood serum or plasma-derived serum. Normal diploid cells require serum to proliferate in culture. Platelet-derived growth factor has been identified as the main serum component responsible f... J Nilsson,J Thyberg -...
通过端粒重复扩增方案(TRAP)检测人类细胞和肿瘤中的端粒酶活性 Detection of telomerase activity in human cells and tumors by a telomeric repeat amplification protocol (TRAP) 用于检测人类白细胞抗原HLA-ABCDRDQ基因分型的试剂盒 人类免疫缺陷病毒抗原、载体、组合物、及其使用方法 相关搜索 与人类有关的抗原 人类...
of their labelling23. This analysis systematically grouped biological samples of the same cell type (Fig.2), similar to array-based clustering of purified human blood cells6. This supports the reproducibility of cell isolation and suggests that three or four replicates of each normal cell type ...