But whether the vascular-bone calcification relationship is an independent association or is simply related to the ageing process and shared risk factors has been unclear. In this issue of Heart, Park and colle
In the absence of clinically recognized cardiovascular disease, increased carotid artery intimal medial thickness was associated with higher hip fracture r
It has been shown that OPG-deficient mice develop both severe osteoporosis and medial calcification of the aorta and renal arteries 9, 10, and they were completely prevented by restoration of the gene [11]. Thus, OPG has been proposed as the link between osteoporosis and atherosclerosis. Further...
Measurement precision was related to the size of structures (CV range 2.5-4.9 % for morphology, 36-44 % for LRNC and calcification). Comparable measurement variability was found between the two platforms on both plaque morphology and tissue composition. In conclusion, good to excellent inter-scan...
Serum amyloid A (SAA) was measured as a marker of systemic inflammation. Paraffin embedded slides of the aortic root were stained to measure total plaque area and to quantify fibrosis, calcification, necrotic core, and inflammatory cells. Results Surgery mice showed a pronounced elevation of serum...
[23]. On preoperative imaging, none of the patients with CH-positive collateral arteries showed signs of atherosclerotic collateral calcification. However, early atherosclerotic pathomechanisms involving CH-positive cells may have already been initiated. Collateral formation is triggered by shear stress, ...
Um et al. [111] explained that people with type 2 diabetes and PDR had a more severe coronary artery calcification and both were more likely to have CHD, compared to patients without DR. Thus, in asymptomatic patients with type 2 diabetes, PDR can be a predictor of CHD. Xu et al. [...
The western diet markedly increases plasmatic VLDL and chylomicrons [56,57] and accelerates the atherogenic process, resulting in the detection of fatty streaks by eight weeks of age and the appearance of complications such as intralesional calcifications [55,65]. In comparison, LDL−/− ...