The Relation between Atherosclerosis Plaque Composition and Plaque RuptureParto BabaniamansourMaryam MohammadiSepideh BabaniamansourEhsan Aliniagerdroudbari
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“foam cells,” which later die and accumulate in the endothelial lining. Other materials are also deposited in the lining, including salts of calcium and other minerals,smooth musclecells, and cellular debris of varyingcomposition. This causes the initially tinylesionsto enlarge and thicken to ...
Arterial stiffness is associated with carotid intraplaque hemorrhage in the general population: the Rotterdam study. OBJECTIVE: The relation between arterial stiffness and atherosclerosis, and specifically the influence of arterial stiffness on plaque composition, is larg... M Selwaness,QVD Bouwhuijsen...
Plaque is a common clinical manifestation of atherosclerosis, leading to reduced blood supply and increasing the risk of heart attack, stroke, and even death [96, 97]. Plaque regression is an important clinical objective for reducing the burden of cardiovascular disease. The single-cell analysis te...
causing plaque formation. Atherosclerotic plaques occur in the subintimal space of blood vessels and are mainly composed of vascular endothelial cells, vascular smooth muscle cells, and immune cells such as macrophages. These cells cause plaque formation through lipid uptake, inflammation, and activation...
Definition and composition of the SASP Regulatory mechanisms of the SASP Through the NF-kB signalling pathway Through the DNA damage reaction Through the p38MAPK signalling pathway Through the m-TOR pathway Through the cGAS-STING signalling pathway Effect of the SASP on atherosclerosis through inflammat...
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μm.n = 3.h,iAnalysis of plaque composition: sections from aortic sinuses were stained with antibodies against CD3 (h, T cells; scale bar, 100 μm) or αSMA (i, smooth muscle cells; scale bar, 200 μm).n = 3.jImmunohistochemical detections of LOX-1 in aortas. Scale...