The combination of atezolizumab (Tecentriq) and bevacizumab (Avastin) continued to display improved survival compared with sorafenib (Nexavar) in previously untreated patients with advanced hepatocellular carcinoma (HCC), according to updated findings from the phase 3 IMbrave150 trial that were presented d...
“The results support the use of atezolizumab and bevacizumab as a practice-changing treatment even amongst older adults with unresectable HCC who have not received prior systemic treatment,” Daneng Li, MD, an assistant clinical professor in the Department of Medical Oncology and Therapeutics ...
Atezolizumab plus chemotherapy with or without bevacizumab in advanced biliary tract cancer: Results from a randomized proof-of-concept phase II trial (IMbrave151).doi:10.1200/JCO.2024.42.3_suppl.435211435#Background:VEGF blockade coupled with cytotoxic chemotherapy can promote an immune-permissive ...
Purpose: To evaluate the addition of the humanized monoclonal antiprogrammed death ligand-1 (PD-L1) antibody, atezolizumab, to platinum-based chemotherapy and bevacizumab in newly diagnosed stage III or IV ovarian cancer (OC). Methods: This multicenter placebo-controlled double-blind randomized phase...
1. Does TPST-1120 in combination with atezolizumab and bevacizumab improve the time that patients are alive and cancer is not growing (progression free survival) compared to atezolizumab and bevacizumab 2. Does TPST-1120 in combination with atezolizumab and bevacizumab improve the shrinking of cancer...
TECENTRIQ, in combination with bevacizumab, is indicated for the treatment of adult patients with unresectable or metastatic hepatocellular carcinoma (HCC) who have not received prior systemic therapy. Unresectable or Metastatic Melanoma TECENTRIQ, in combination with cobimetinib and vemurafenib, is indicated...
Used in combination to treat Unresectable hepatocellular carcinoma (hcc) Regimen in combination with: Bevacizumab (DB00112) •••••••••••• ••••• ••••••••• ••••• Used in combination to treat Unresectable melanoma Regim...
Adults with a type of liver cancer called hepatocellular carcinoma (HCC). TECENTRIQ may be used with the medicine bevacizumab when your liver cancer: has spread or cannot be removed by surgery, and you have not received other medicines by mouth or injection through your vein (IV) to treat yo...
the patient was transferred to a rehabilitation facility. No anti-cancer chemotherapy was restarted due to poor clinical status. The patient died frommultiple organ failure67days after atezolizumab/bevacizumab initiation. The authors reviewed five other reported cases of atezolizumab-induced encephalitis in...
Unresectable or Metastatic Hepatocellular Carcinoma TECENTRIQ, in combination with bevacizumab, is indicated for the treatment of adult patients with unresectable or metastatic hepatocellular carcinoma (HCC) who have not received prior systemic therapy. Unresectable or Metastatic Melanoma TECENTRIQ, in combinati...