A possible pharmacokinetic interaction of atenolol or metoprolol and piroxicam was investigated over a period of 7 days. The mean plasma concentration versus time curve of atenolol (n=6) was nearly uninfluenced, whereas the mean metoprolol concentrations (n=6) were enhanced (statistically not signifi...
A possible pharmacokinetic interaction of atenolol or metoprolol and piroxicam was investigated over a period of 7 days. The mean plasma concentration versus time curve of atenolol (n=6) was nearly uninfluenced, whereas the mean metoprolol concentrations (n=6) were enhanced (statistically not ...
Metoprolol Metoprolol may increase the arrhythmogenic activities of Atenolol. Metyrosine Atenolol may increase the hypotensive activities of Metyrosine. Mexiletine Atenolol may increase the arrhythmogenic activities of Mexiletine. Mianserin Mianserin may decrease the antihypertensive activities of Atenolol. Miconazo...
Pharmacokinetics of metoprolol, propranolol, and atenolol were investigated in six healthy volunteers following 7 days of oral monotherapy with these drugs, and after 7 days concurrent administration of each of these betareceptor antagonists with cimetidine. Application of cimetidine did not lead to any...
However, a reverse trend (α and Rs) was observed for atenolol with increase in temperature. The thermodynamic data from van't Hoff plots revealed that the enantioseparation was enthalpy driven for metoprolol and propranolol while entropy driven for atenolol. To understand the mechanism of chiral ...
(M/P ratio of ≈2). In addition to its relatively high excretion into milk,immaturityof renal function of infant was probably one of the contributing factors to the toxicity in this case.Propranolol, digitalis,metoprolol,captopril, anddiureticsthat are slightly acidic have low concentrations in ...
Egginger G,Lindner W,Vandenbosch C,et al.Enantioselective bioanalysis of beta-blocking agents: focus on atenolol,betaxolol, carvedilol, metoprolol, pindolol, propranolol and sotalol.Biomedical Chromatography. 1993Egginger, G., Lindner, W., Vandenbosch, C., and Massart, D. L., Enantioselective ...
Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. European Journal of Clinical PharmacologyGreefhorst APM, van Herwaarden CLA (1982) Ventilatory and haemodynamic effects of terbutaline infusion during beta ...
(1982). Interaction of metoprolol, propranolol and atenolol with concurrent adminis- tration of cimetidine. Klin. Wochenschr., 60, 1401-1407.Kirch W, Spahn H, Köhler H, et al. Interaction of metoprolol, propranolol and atenolol with concurrent administration of cimetidine. Klin Wochenschr 1982;...
Seven of the most popular beta-blockers were chosen as representatives: atenolol; betaxolol; carvedilol; metoprolol; pindolol; propranolol; and sotalol, these span the whole range of lipophilicity to hydrophilicity (polarity). Enantioselective HPLC bioassays for these -blockers published so far, ...