Evidence at the protein level for nesprin-2-epsilon-1 in Ntera-2 and ESC cells and for nesprin-2-epsilon-2 in heart and brain.Nguyen Thuy DuongGlenn E. MorrisLe Thanh LamQiuping ZhangCaroline A. SewryCatherine M. ShanahanIan Holt...
A tool to analyze synteny at the protein level. We develop an algorithm to detect statistically significant clusters of exons between two proteomes. The tool provides algorithms to quickly detect and visualize results in order to support conclusions from genomic data. The method discovers clusters of...
Comparison of Protein and mRNA Expression Evolution in Humans and Chimpanzees Even though mRNA expression levels are commonly used as a proxy for estimating functional differences that occur at the protein level, the relation between... N Fu,D Ines,K Janet,... - 《Plos One》 被引量: 219发表...
State-of-the-art super-resolution microscopy allows researchers to spatially resolve single proteins in dense clusters. However, accurate quantification of protein organization and stoichiometries requires a general method to evaluate absolute binder lab
7a), with parallel decreases at the protein level (Fig. 3a). More severe transcriptional attenuation of these oncogenes was noted upon BRD4 degradation by ZBC-260, with AU-15330 specifically abolishing expression of additional driver oncogenes (Extended Data Fig. 7b), again suggesting a distinct...
We classified the main cell types of thymocytes and identified three subtypes in the DP stage. We then developed a flow cytometry gating strategy to partition these DP subtypes at the protein level. Based on unsupervised classification and pseudotime analysis, we found that DP thymocytes undergo an...
We also find evidence that the fluctuations in LuxO levels are dominated by intrinsic noise. We furthermore propose LuxO and LuxR interact at all autoinducer levels via an unknown mechanism. Of importance, our new method of evaluating correlations at the microcolony level is unaffected by ...
These sequences were found to be well conserved at the nucleotide level (41 to 52%), and even more conserved at the the protein level (71 to 78%). Corresponding ORF and 3' UTRs were amplified by RT-PCR from lines A188 and LC, respectively. All cloned sequences were identical to ...
protein sparing actio protein tools protein-free blood fi proteinfoods proteinisolate proteinkinase ue protention protentomid protest slogans protestantism in ital protestantismo protestantophobia protestzug protfolio assessment prothalamion protheses and implant prothrombin time pt prothrombin timept protidepro...
Since CXCL12 is a key chemokine in the pathogenesis of myeloma17,18 we used ELISA and IHC to validate expression differences at the protein level. Of note, we did not find a consistent down-regulation of CXCL12 in sorted MM cells from focal lesions using ELISA (n = 6 patients, mean...