common in literature to evaluate the stability by measuring the melting temperature12. It is defined as the temperature at which equal amounts of protein are folded and unfolded under the given conditions. Different methods to determine the melting temperature have been described which all share the...
The γ-carboxylation of glutamate residues enables Ca2+-mediated membrane assembly of protein complexes that support broad physiological functions including hemostasis, calcium homeostasis, immune response, and endocrine regulation1-4. Modulating γ-carboxylation level provides prevalent treatments for hemorrhagic...
Whey protein is a high-quality protein from cow's milk, containing all of the essential amino acids. Milk is composed of two forms of protein: casein protein (80%) and whey protein (20%). Whey protein is more soluble than casein protein and is of a higher quality. It ...
In health, ferroptosis helps eliminate cancer cells. Unlike other types of programmed cell death, ferroptosis depends on iron accumulating in a cell. That triggers the rapid generation of reactive oxygen species, which destroy...
These researchers published more than 200 health-related papers and deposited more than 400 structure coordinates in the Protein Data Bank during this period. The summaries presented in this review highlight a representative selection of this research, covering a range of health issues including; ...
The maturation of single-cell transcriptomic technologies has facilitated the generation of comprehensive cellular atlases from whole embryos1–4. A majority of these data, however, has been collected from wild-type embryos without an appreciation for th
The prevalence of polycystic ovary syndrome in reproductive-aged women of different ethnicity: a systematic review and meta-analysis. Oncotarget. 2017;8:9635. Google Scholar Baskind NE, Balen AH. Hypothalamic-pituitary, ovarian and adrenal contributions to polycystic ovary syndrome. Best Pract Res ...
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Yet, the down-regulation of CXCL12 could not be validated at the protein level, probably due to an enrichment of CXCL12-producing cells in the TME of focal lesions and internalization of this cytokine by MM cells. Tumor subclones show different levels of spatial transcriptional plasticity The ...
Multivalent interactions facilitate motor-dependent protein accumulation at growing microtubule plus-ends Renu Maan Louis Reese Marileen Dogterom Nature Cell Biology Article Open Access 19 Dec 2022 +TIPs condense on microtubule plus-ends Bernardo Gouveia Sabine Petry Nature Cell Biology News & Vi...