n = 13,390 (SII),n = 6,351 (SIII); stalk cells:n = 4,399 (SI),n = 3,361 (SII),n = 5,517 (SIII)). Data are mean ± s.e.m.i, Radar plot showing the scaled activities of TAPFs.j, Illustration of the putative process of tumour angiogenesis.k,...
As neovascularization elongates (through angiogenic stages SI, SII and SIII), APLN+ tip cells at the SI stage (APLN+ TipSI) advanced to TipSIII cells with increased Notch signalling. Meanwhile, stalk cells, following tip cells, transitioned from high chemokine expression to elevated TEK (also ...
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